【作者】 陈蕊；

【导师】 周稚仙； 杜晨霞；

【作者基本信息】 郑州大学 ， 无机化学， 2003， 硕士

【摘要】 本文研究了三种新型杯[4]芳烃衍生物5，11，17，23-四叔丁基-25，26，27，28-四-[3-（甲氧基羰基）苄氧基]杯[4]芳烃（Ⅰ）和5，11，17，23-四叔丁基-25，26，27，28-四-[3-（乙氧基羰基）苄氧基]杯[4]芳烃（Ⅱ）和25，26，27，28-四-[3-（甲氧基羰基）苄氧基]杯[4]芳烃（Ⅲ）为载体的PVC膜电极的响应行为；实验结果表明，三种电极对季铵盐正离子均具有优良的能斯特电位响应性能，以（Ⅰ）为载体的电极对Bu₄N⁺、Et₄N⁺和Me₄N⁺的线性响应范围分别为10^-6～10^-1，10^-6～10^-1和10^-4～10^-1mol／L，相应的斜率为59.2，55.0和55.9mV／pc，相应的线性回归系数为0.9999，0.9993和0.9999；以（Ⅱ）为载体的电极对Bu₄N⁺、Et₄N⁺和Me₄N⁺的线性响应范围分别为10^-6～10^-1，10^-5～10^-1和10^-4～10^-1mol／L，相应的斜率为59.8，56.6和56.0mV／pc，相应的线性回归系数为0.9996，0.9999和0.9999；以（Ⅲ）为载体的电极对Bu₄N⁺、Et₄N⁺和Me₄N⁺线性响应范围分别为10^-6～10^-1，10^-6～10^-1和10^-4～10^-1，相应的斜率为58.1，54.6，55.5mV／pc，相应的线性回归系数为0.9999，0.9996和0.9999。电极具有读数稳定，重复性好，可在pH值较宽范围内测定等优点。用上述三种电极测定了药品溴丙胺太林片中溴丙胺太林的含量，所得结果均与药典法基本一致。更多还原

【Abstract】 The response characteristics of three novel PVC membrane ion-selective electrodes based on 5,11,17,23- tetra- ten- butyl- 25,26,27,28- tetrakis [3-(methoxycarbonyl) benzyloxy] calix[4] arene ( I ) and 5,11,17,23- tetra- tert- butyl-25,26,27,28- tetrakis [3- (ethoxycarbonyl) benzyloxy] calix[4] arene ( II ) and25,26,27,28- tetrakis [3- (methoxycarbonyl) benzyloxy] calix[4] arene ( III ) as carriers were investigated. The electrodes exhibit almost Nernst response characteristics for Bu4N+, Et4N+ and Me4N+. The linear response ranges of the electrode based on ( I) towards Bii4N+, Et4N+ and Me4N+ are 10-6-10-1,10-6~10-1, 10-4~10-1 mol/ L and the corresponding slopes are 59.2,55.0 and 55.9 mV/ pc with correlation coefficients of 0.9999, 0.9993 and 0.9999, respectively; the linear response ranges of electrode based on ( II ) towards Bu4N4, Et4N+ and Me4N+ are 10-6~10-1, 10-5-10-1,10-4~10-1 mol/ L and the corresponding slopes are 59.8,56.6 and 56.0 mV/ pc with correlation coefficients of 0.9996, 0.9999 and 0.9999, respectively; the linear response ranges of electrode based on (III ) towards Bu4N+, Et,N+ and Me4N+ are lO^lO’1,10’6~10’’, lO^-lO’1 mol/ L and the corresponding slopes are 58.1,54.6 and 55.5 mV/ pc with correlation coefficients of 0.9999, 0.9996 and 0.9999, respectively. The electrodes have advantages of stability, repeatability and wider pH range. The electrodes were applied to the content assay of propantheline bromide tablets. The results obtained are in agreement with that determined by the pharmacopoeia method.更多还原