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Wistar大鼠肠系膜淋巴管的发生及形态学研究

Study on Development and Morphology of the Mesenteric Lymphatics in Wistar Rat

【作者】 徐军

【导师】 邵旭建;

【作者基本信息】 青岛大学 , 人体解剖学, 2003, 硕士

【摘要】 目的 探讨Wistar大鼠肠系膜淋巴管的发生及形态学特点。 方法 应用普通光学显微镜、酶组织化学、透射电子显微镜(TEM)及淋巴管膀胺天蓝活体注射法对Wistar大鼠肠系膜淋巴管的发生及形态学进行研究。 结果 (1)胚胎16天,小肠系膜血液循环已建立;胚胎期连续追踪观察没有发现血管“出芽”并分化成淋巴管管道。 (2)胚胎18天,肠系膜淋巴管形成;生后0天,淋巴管瓣膜出现。 (3)肠系膜淋巴管的配布因部位不同而有所差异。 (4)胚胎期与成年期肠系膜淋巴管内皮的超微结构有明显差异。 结论(1)没有发现肠系膜血管分化形成淋巴管,淋巴管可能发生于血管以外的间充质细胞,即“向心”性发生。 (2)肠系膜淋巴管因部位不同而存在着明显的形态和结构上的差异,这是与其功能相适应的。 (3)胚胎期和成年期血管上的碱性磷酸酶系统可能存在着一定的差异。

【Abstract】 Objective To investigate the developmental and morphologicalcharacters of the mesenteric lymphatics in Wistar rat.Methods The developmental and morphological characters of the mesenteric lymphatics of 183 Wistar rats were studied by using light microscope, en2yme-histochemistry, TEM and injection of Pontamine sky blue.Results (1) The blood circulation of mesentery was established on day 16 during pregnancy, but no "sprout" was found from the blood vessels and then formed the lymphatics during the period of pregnancy.(2) The mesenteric lymphatics appeared on day 18 during pregnancy and the valves appeared on day 0 after birth.(3) The distribution of mesenteric lymphatics varied on different mesenteric parts and ages.(4) There were obvious differences in ultrastructure of the lymphatic endothelia between the embryonic and the adult rats.Conclusion (1) No blood vessels were found to differentiate and become the lymphatics in the mesentery of fistar rat, and this suggested that the lymphatic might develop from the mesenchymalcells in the tissue. Our results showed the mesenteric lymphatics developed "centripetally" .(2) There were obvious morphological differences for the mesenteric lymphatics in the different parts, and this illustrated that the structural character decided the function.(3) There might be some differences of ALPase system in the blood vessels between the embryonic and the adult rats.

【关键词】 Wistar大鼠肠系膜淋巴管发生形态学
【Key words】 Wistar ratmesenterylymphaticdevelopmentmorphology
  • 【网络出版投稿人】 青岛大学
  • 【网络出版年期】2004年 01期
  • 【分类号】R329
  • 【下载频次】94
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