【作者】 白靖宇；

【导师】 俞昌德； 吴炳煌； 吴钢；

【作者基本信息】 福建中医学院 ， 针灸推拿学， 2002， 硕士

【摘要】 目的： 探讨针刺颅骨缝区(颅针)对急性脑梗塞(CI)患者临床神经功能恢复及血浆内血小板膜糖蛋白(GMP-140)的影响。 方法： 采用针刺颅骨缝区治疗30例急性脑梗塞患者及单纯药物治疗30例急性CI患者，对照观察临床神经功能缺损评分值及血浆GMP-140含量变化。 结果： (1)脑梗塞患者急性期血浆内GMP-140含量较正常值明显增高； (2)单纯药物组和颅针加药物组治疗后临床神经功能缺损评分值及血浆GMP-140含量均显著降低(p＜0.01)，颅针加药物组临床神经功能缺损评分值及GMP-140水平较单纯药物组下降明显(p＜0.05)，有显著性差异； (3)治疗前后神经功能缺损评分值与血浆GMP-140水平呈中度正相关。 2002届硕土研究生毕业论又结论：门）脑梗塞患者急性期存在血小板活化、释放增多；（2）单纯药物治疗与颅针加药物治疗急性Q患者均可改善11名床神经功能、抑制血小板活化；而颅针加药物组疗效优于单纯药物组；门）血浆 GMPl 水平可作为急性＊患者病情轻重的客观指标和治疗效果评判指标。更多还原

【Abstract】 Objective:Towards the skull needling effecting to the plasma GMP-140 andthe improvement of scores of clinical nervous function on acutecerebral infarction.Method:30 cases were treated with the skull needling combined withmedicines, and another 30 cases were treated with routinemedicines only. The variety of plasma’s GMP-140 and scores ofclinical nervous function were investigated.Results:(1) Compared with normal level, GMP-140 level in acute CI patients increased.(2) In both two groups, the significant decreasing was observed in scores of clinical nervous function and plasma GMP-140(P<0.01);Plasma GMP-140 and scores of clinical nervous function in skullneedling group decreased much significantly than that in medicinetreating group (P<0.05).(3) Plasma GMP-140 concentration were positively correlated withthe scores of clinical nervous function.Conclusions:(1) It is suggested that platelet activity in CI patients increases in early stage.(2) Both the skull needling and medicine treatment can obviously improve scores of clinical nervous function and reduce platelet activity; The therapeutic effect in skull needling combined medicine treatment group is superior to that in medicine treatment group;(3) Plasma GMP-140 reflects the degree of the concentration of damage in acute Cl patient更多还原