【作者】 李霞；

【导师】 魏博源； 谭少健；

【作者基本信息】 广西医科大学 ， 人体解剖与组织胚胎学， 2002， 硕士

【摘要】 目的　比较多焦点人工晶体（MIOL）眼与单焦点人工晶体（SIOL）眼的视功能状况，评价多焦点人工晶体植入的有效性及安全性。为完善MIOL植入提供成功经验。　方法　从我院住院的老年性白内障患者中选择合适的病例44例（60只眼），随机分为两组，每组30眼，行超声乳化白内障吸出术，MIOL组植入AMO Array SA40N ，SIOL组植入Allergan SI40NB。术后1d、1w、1m、3m对患者进行远近视力、对比敏感度（CS）、色觉、立体视锐度、视野等视功能的检查，并检测术眼的屈光状态及拟调节力，问卷调查视物情况及视觉症状。　结果　MIOL眼具有与SIOL眼一样良好的非矫正远视力，非矫正近视力明显优于SIOL眼（分别为0.86±0.27、0.45±0.14，P<0.05）；两组病人CS在低、中空间频段均位于正常范围内，高空间频段则均稍下降，差异无显著性（P>0.05）；MIOL眼立体视觉优于SIOL眼，尤其是双眼植入MIOL者；两组病人色觉无异常；自动视野计检查发现MIOL组1例（1眼）视野缺损，其余患者视野正常；MIOL眼焦深大于SIOL眼，分别为+1.0D～－3.5D、+1.0D～－1.0D；绝大多数患者对手术效果满意，MIOL组近距离作业满意度高于SIOL组（P<0.05）；两组病人视觉症状均较少（P>0.05）。　结论　MIOL植入安全而有效，可以提供与SIOL一样良好的远视力，及更好的近视力及立体视觉、更广的焦深、较低的戴近用镜率及较高的病人满意度。更多还原

【Abstract】 Objective Comparing the vision function of the multifocal intraocular lens(MIOL) eye with monofocal intraocular lens(SIOL) eye in order to evaluate the effectiveness and safety of the MIOL.　Methods 　In this study, 44 senile cataract patients (60 eyes) were devided into two groups randomly: Group MIOL and Group SIOL. Each group included 30 eyes. All the patients accepted phacoemulsification and MIOL/SIOL implantation. The MIOL we used is AMO Array SA40N while the SIOL is Allergan SI40NB. Vision function including distance visual acuity (DVA), near visual acuity (NVA), contrast sensitivity (CS), color vision , visual field and stereopsis acuity were measured in 1d, 1w, 1m,3m postoperatively. The refraction and the pseudoaccommodation were also detected. Visual symptoms were observed by questionnaire.　Results MIOL eye showed excellent DVA as SIOL eye (1.00±0.27 versus 0.89±0.23，P>0.05) and better NVA than the later (0.86±0.27、0.45±0.14，P<0.05). The CS of both groups were within the reference range and were identical at 1.5,3 and 6 cpd spatial frequencies. At 12 and 18 cpd, the CS of the two groups lower than reference range. MIOL eye has better stereoscopic vision than the SIOL one, especially for biltateral MIOL implantaion. All the patients’ color vision are good and all the patients’ visual field are in normal range except for one man (1 eye) having the defect in the lower-nazal quadrant because of retinal vascular disease. MIOL provided better pseudoaccommodation than SIOL, the depth of focus were +1.0D~-3.5D, +1.0D~-1.0D respectively. Most patients were satisfied with the result of the operation but higher satisfaction was found in MIOL group when near task was asked. Conclusion MIOL is safe and effective. It can provide good DVA as the SIOL does, but better NVA and stereoscopic vision, less glasses use and higher satisfaction than the latter.更多还原