【作者】 谭机永；

【导师】 谢志春；

【作者基本信息】 广西医科大学 ， 流行病与卫生统计学， 2002， 硕士

【摘要】 目的：评价叶下珠和复方叶下珠治疗无症状乙肝病毒携带者的疗效。方法：采用随机、双盲法将191例无症状携带者分成3组，叶下珠组72人，复方叶下珠组73人，对照组46人，治疗3个月。结果：叶下珠组与复方叶下珠组HBsAg滴度平均分别下降了1.57和1.66个对数，对照组则平均上升了0.45个对数，两组的HBeAg转阴率分别是34.5%和35.9%，与对照组的3.0%相比有显著性差异(均是p<0.01)。患者经复方叶下珠治疗后的HBV－DNA含量明显下降(p<0.01)。结论：叶下珠和复方叶下珠均有较强的抑制HBV作用。更多还原

【Abstract】 Objective： To evaluate the effect of phyllanthus urinaria (PU) and It’s compound (PUC) on symptomless carriers of hepatitis B virus. Methods: 191 patients with symptomless carriers were randomly divided into three groups. 72 patients and 73 patients were treated three months with PU and PUC respectively. The control group included 46 patients. Result: the level of HBsAg descended averagely 1.57Log and 1.66Log respectively in PU group and PUC group, while in control group enhanced averagely 0.45Log. 34.5% and 35.9% of patients in PU group and PUC group respectively lost their HBeAg (while control was 3.0%). The level of HBV-DNA in PUC group after treatment were descended remarkably. Conclusion: The results indicate that PU and PUC can inhibit HBV.更多还原