健脾益肾、化瘀通络法治疗慢性肾炎的组方配伍理论探讨

【作者】 任建素；

【导师】 孙美珍；

【作者基本信息】 南京中医药大学 ， 方剂学， 2001， 硕士

【摘要】 本文根据历代医家对于慢性肾炎辨证论治理论以及临床观察，认为脾肾气（阳）虚、瘀血阻络是慢性肾炎的基本病机，提出健脾益肾、化瘀通络是治疗慢性肾炎的的基本大法。通过对古今相关方剂的筛选、整理与分析，发现治疗慢性肾炎方剂的组成以健脾益肾、化瘀通络药为主，常配伍利水渗湿药、清热药、理气药、温里药、解表药等，并对其组方理论进行探讨，同时对组方结构中的每类药物进行了归纳与分析。 在此理论指导下，依据健脾益肾、化瘀通络法组方，拟定“慢肾汤”，治疗31例慢性肾炎，结果总有效率达90.3％，优于对照组。该方对慢性肾炎主要症状、体征、理化指标具有明显的改善作用，与对照组相比有显著差异。更多还原

【Abstract】 According to the theory of treating diseases based on differentiation of symptoms and signs and clinical observation of chronic glomerulo- nephritis(CGN) in all ages, the author points out that the basic pathogenesis are yang or qi deficiency in both the spleen and kidney and blood stasis in the collaterals. The main therapeutic principle for the disease is to strengthen the spleen, nourish the kidney and remove blood stasis from collaterals. Through the analysis of relevant prescriptions of all ages, the author thinks the main ingredients of the prescriptions for the disease should include those to strengthen the spleen, nourish the kidney and remove blood stasis from collaterals, such as drugs for inducing diuresis and excreting dampness,heat-clearing drugs, drugs for regulating qi,interior-warming drugs,drugs for treating exterior syndromes etc.The author also analyzes the most frequently used herds used in these prescriptions. Guided by this theory, MAN SHEN TANG was formulated and used in the treatment of 31 cases of CGN,with its total effective rate of 90.3%,higher than that in the control group.It can effectively relieve the main symptoms and sign and markedly improve the physical and chemical index of CGN,with significant difference from the control group.更多还原