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基于“态靶辨治”理论构建失眠障碍的临证策略

Clinical strategies for insomnia disorder based on the "state-target differentiation" theory

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【作者】 刘家博晋胜康杨玲玲谢晓燕张卓李昀熹溥弋棋杜锦程李艳

【Author】 LIU Jiabo;JIN Shengkang;YANG Lingling;XIE Xiaoyan;ZHANG Zhuo;LI Yunxi;PU Yiqi;DU Jincheng;LI Yan;The Second Clinical Medical College of Guangzhou University of Chinese Medicine;Department of Psychological Sleep, Guangdong Hospital of Traditional Chinese Medicine;

【通讯作者】 李艳;

【机构】 广州中医药大学第二临床医学院广东省中医院心理睡眠科

【摘要】 失眠障碍(ID)显著降低患者生活质量并诱发共病风险,涉及交感神经与副交感神经平衡、神经内分泌免疫紊乱、睡眠卫生作息、睡眠时相紊乱、医源性、药源性、遗传因素、精神心理因素等复杂因素,诊疗难度大,疗效欠佳。当前中医诊疗体系对失眠病因病机阐释尚有待深化。应用仝小林“态靶辨治”理论,结合体质特点、起病时间及症状程度等因素,建立失眠障碍“倦”“热”“湿”“燥”“虚”五态分类模型。在该模型指导下,治疗上遵循“遵态选方,依症施治”原则,构建“病-态-方-药”四级诊疗路径,以期为临床诊疗失眠障碍提供新思路与新方法。

【Abstract】 As the second prominent mental health issue in the world, insomnia disorder(ID) can significantly affect patients’ quality of life and increase comorbidity risks during its chronic progression. However, the current TCM diagnostic frameworks offer limited explorations into its etiology and pathogenesis. This study innovatively applies the "state-target differentiation" theory proposed by Academician Tong Xiaolin to establish a novel clinical strategy for the disease. By taking into account factors such as constitutions, disease onset, and symptom severity, the study constructs a five-state classification model(fatigue, heat, dampness, dryness, and deficiency). Guided by the identified states, therapies are tailored through formula selection based on the state-and symptom-specific treatment, thereby establishing a four-level diagnostic and therapeutic pathway of "disease-state-formula-medication". This approach aims to provide new perspectives and methodologies for the clinical management of insomnia disorder.

【基金】 国家自然科学基金资助项目(82305167);广东省基础与应用基础研究基金项目(2023A1515220036);省部共建中医湿证国家重点实验室2024年度揭榜挂帅开放课题(SZ2024KF12)
  • 【文献出处】 吉林中医药 ,Jilin Journal of Chinese Medicine , 编辑部邮箱 ,2026年03期
  • 【分类号】R256.23
  • 【下载频次】33
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