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施杞从“瘀”论治慢性腰痛的临床经验及现代研究

Clinical Experience and Modern Research of Professor Shi Qi in Treating Chronic Low Back Pain from the Perspective of “Blood Stasis”

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【作者】 倪国栋彭生李诗翩苗成马增斌施杞郑志坚孙悦礼王拥军

【Author】 NI Guodong;PENG Sheng;LI Shipian;MIAO Cheng;MA Zengbin;SHI Qi;ZHENG Zhijian;SUN Yueli;WANG Yongjun;Shanghai University of Traditional Chinese Medicine;Longhua Hospital,Shanghai University of Traditional Chinese Medicine;Beijing Hospital/National Center for Gerontology/National Clinical Research Center for Gerontology/Institute of Geriatric Medicine,Chinese Academy of Medical Sciences;Shanghai Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;

【通讯作者】 孙悦礼;王拥军;

【机构】 上海中医药大学上海中医药大学附属龙华医院北京医院/国家老年医学中心/老年疾病国家临床医学研究中心/中国医学科学院老年医学研究院上海中医药大学附属岳阳中西医结合医院

【摘要】 慢性腰痛是全球范围内高发的慢性疾病之一,传统中医药学和现代医学均从不同角度对其病因及治疗进行了系统探索。国医大师施杞教授在“气虚血瘀”的中医经典理论基础上,融合现代生物力学、分子生物学等成果,提出“益气化瘀法”,为慢性腰痛的病因认识、诊断评估及综合防治提供了新的理论框架与临床路径。通过整合现代影像技术与生物标志物检测,有助于实现个性化诊疗,凸显气血调和与整体动态观在临床中的重要价值。基于瘀血理论创制的“筋痹方”在缓解腰部疼痛、改善腰椎功能等方面展现出显著的临床疗效。未来研究应进一步加强分子机制的解析,优化个体化治疗策略,开展高质量的临床试验研究,以推动中医药在慢性腰痛防治中的现代化与国际化发展。

【Abstract】 Chronic low back pain is one of the most prevalent chronic conditions worldwide. Both traditional Chinese medicine(TCM) and modern medicine have systematically explored its etiology and treatment from different perspectives.Professor Shi Qi,a master of TCM,builds upon the classical theory of “Qi deficiency and blood stasis” and integrates advances in modern disciplines such as biomechanics and molecular biology to propose the method of “benefiting Qi and activating blood circulation”. This approach provides a novel theoretical framework and clinical pathway for understanding the etiology,diagnostic evaluation,and comprehensive management of chronic low back pain. By incorporating modern imaging techniques and biomarker detection,this approach facilitates individualized diagnosis and treatment,highlighting the clinical significance of harmonizing Qi and blood as well as maintaining a holistic and dynamic perspective. The herbal formula “Jin Bi Fang”,developed based on blood stasis theory,has demonstrated significant clinical efficacy in alleviating low back pain and improving lumbar function. Future research should elucidate the underlying molecular mechanisms,optimize individualized therapeutic strategies,and conduct high-quality clinical trials to promote the modernization and internationalization of TCM in the prevention and treatment of chronic low back pain.

【基金】 首都卫生发展科研专项(首发2026-2-40510);中央高水平医院临床科研业务项目(BJ-2024-205);北京中医药大学教育教学改革专项(XJZ25049);国家重点研发计划项目(2024YFC3507401);国家自然科学基金面上项目(81273849);上海市重大临床研究项目(SHDC2020CR1010A)
  • 【文献出处】 中国中医基础医学杂志 ,Journal of Basic Chinese Medicine , 编辑部邮箱 ,2026年05期
  • 【分类号】R249;R274.9
  • 【下载频次】37
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