【摘要】 目的 研究上消化道早癌活检和内镜黏膜下剥离术(ESD)术后病理检出率的差异性。方法 选取74例患者(食道肿瘤患者32例,胃肿瘤患者40例,非肿瘤患者2例),均实施上消化道早癌活检、ESD术后病理检查。分析术后及术前不同疾病类型(非肿瘤、低级别上皮内瘤变、高级别上皮内瘤变、黏膜内癌、黏膜下层癌)活检一致性。结果 术前及术后检出一致性分析显示：非肿瘤检出一致有2例,低级别上皮内瘤变检出一致有19例,高级别上皮内瘤变检出一致有12例,黏膜内癌检出一致有2例。低级别上皮内瘤变术前及术后一致例数为19例。高级别上皮内瘤变术前及术后一致例数为12例。黏膜内癌术前及术后一致例数为2例。结论 上消化道早癌活检存在一定局限性, ESD术后病理诊断价值均较高,建议结合实际选择联合诊断方式。更多还原

【Abstract】 Objective To study the difference of detection rates of biopsy and postoperative pathology of endoscopic submucosal dissection(ESD) for early upper gastrointestinal cancer. Methods All 74 patients(32 cases with esophageal tumors, 40 cases with gastric tumors, and 2 cases without tumors) underwent early biopsy of upper gastrointestinal cancer and post-ESD pathological examination. The consistency of biopsy results between postoperative and preoperative stages was analyzed across different disease types(non-neoplastic, lowgrade intraepithelial neoplasia, high-grade intraepithelial neoplasia, intramucosal carcinoma, and submucosal carcinoma). Results The consistency analysis between preoperative and postoperative pathological findings revealed the following consistency cases: 2 cases of non-neoplastic lesions, 19 cases of low-grade intraepithelial neoplasia, 12 cases of high-grade intraepithelial neoplasia, and 2 cases of intramucosal carcinoma. Consistency between pre-and post-operative diagnosis was observed in 19 cases of low-grade intraepithelial neoplasia, 12 cases of high-grade intraepithelial neoplasia, and 2 cases of intramucosal carcinoma. Conclusion Biopsy of early upper gastrointestinal cancer has certain limitations, and the diagnostic value of post-ESD pathology is relatively high. It is recommended to choose the combined diagnostic method in combination with the actual situation.更多还原