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脊柱肿瘤的外科治疗研究进展
Research progress in surgical treatment of spinal tumors
【摘要】 脊柱肿瘤为临床常见肿瘤,临床表现主要有:脊柱结构破坏致脊柱不稳,神经根及脊髓受压引发剧烈疼痛,夜间疼痛加重,严重者可出现截瘫。临床实践中,明确肿瘤起源、病理性质及疼痛机制至关重要。脊柱肿瘤性疼痛的治疗以药物、手术及物理治疗为主,其中药物治疗作用有限,外科手术更能提升疗效与患者生活质量。目前主流术式包括经椎弓根椎体切除术、射频消融术、放射性粒子植入近距离照射治疗、内镜手术及术中辅助技术,需根据患者个体情况与临床需求选择。本文就5种外科治疗方法的临床应用现状加以综述,供临床参考。
【Abstract】 Spinal tumors represent a prevalent clinical entity, characterized by distinct clinical manifestations including spinal instability due to structural compromise, severe pain resulting from nerve root and spinal cord compression, nocturnal exacerbation of pain, and potential paraplegia in advanced cases. In clinical practice, it is imperative to ascertain the tumor’s origin, pathological nature, and pain mechanisms. The therapeutic approach to spinal tumor-related pain primarily encompasses pharmacological interventions, surgical procedures,and physical therapy. While pharmacological management has limited efficacy, surgical interventions demonstrate superior outcomes in improving both therapeutic efficacy and patients’ quality of life. Current mainstream surgical modalities include transpedicular corpectomy, radiofrequency ablation, brachytherapy with radioactive particle implantation, endoscopic surgery, and intraoperative auxiliary techniques based on individual patient characteristics and clinical requirements. This article provides a comprehensive review of the current clinical applications of these five surgical treatment modalities, offering valuable insights for clinical reference.
【Key words】 spinal neoplasms; surgical treatment; minimally invasive surgery; radiotherapy; assistive technique;
- 【文献出处】 中国矫形外科杂志 ,Orthopedic Journal of China , 编辑部邮箱 ,2026年11期
- 【分类号】R738.1
- 【下载频次】56