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卵巢子宫内膜异位囊肿术后复发的临床特点与影响因素分析

Analysis of clinical characteristics and influencing factors of postoperative recurrence of ovarian endometriosis

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【作者】 陆志灵唐菲李婉晴何晔郭培培叶伟吴荣魏兆莲

【Author】 LU Zhi-ling;TANG Fei;LI Wan-qing;HE Ye;GUO Pei-pei;Ye Wei;WU Rong;WEI Zhao-lian;The First Affiliated Hospital of Anhui Medical University;Chaohu Hospital Affiliated to Anhui Medical University;

【通讯作者】 魏兆莲;

【机构】 安徽医科大学第一附属医院安徽医科大学附属巢湖医院

【摘要】 目的 探讨卵巢子宫内膜异位囊肿(OMA)术后复发特点及影响因素。方法 基于回顾性分析2018年1月至2023年1月在安徽医科大学第一附属手术治疗的475例OMA,其中术后复发227例为研究组,术后未复发248例为对照组。结果 合并子宫肌瘤[比值比(OR)=1.823,95%置信区间(CI)1.072~3.100]、双侧OMA(OR=1.968,95%CI 1.132~3.421)、伴随临床症状(OR=2.491,95%CI 1.553~3.995)、月经分泌期手术(OR=1.930,95%CI 1.253~2.973)、子宫内膜异位症手术分期高(OR=1.588,95%CI 1.204~2.095)及原发囊肿大(OR=1.139,95%CI 1.027~1.263)增加术后复发的概率;高血红蛋白(Hb)(OR=0.982,95%CI 0.967~0.999)、术后药物治疗(OR=0.220,95%CI 0.126~0.384)及术后生育(OR=0.507,95%CI 0.290~0.887)降低术后复发的概率。原发单侧术后易复发于原发侧,原发双侧术后易复发于左侧。结论 合并子宫肌瘤、双侧OMA、伴随临床症状、月经分泌期手术、子宫内膜异位症手术分期高、原发囊肿大是OMA术后复发的独立危险因素。高Hb、术后药物治疗及术后生育是术后复发的保护因素。原发性OMA与复发性OMA的侧别分布有一定相关性。

【Abstract】 ObjectiveTo analyze the characteristics and influencing factors of postoperative recurrence of ovarian endometrioma.MethodsA retrospective analysis was performed on 475 patients with OMA who were treated in the First Affiliated Hospital of Anhui Medical University from January 2018 to January 2023, with 227 patients with postoperative recurrence in the study group and 248 with no recurrence in the control group.ResultsCombination with uterine fibroids(OR=1.823,95%CI 1.072-3.100),bilateral OMA(OR=1.968,95%CI 1.132-3.421),being accompanied by clinical symptoms(OR=2.491,95%CI 1.553-3.995),surgery during menstrual secretion(OR=1.930,95%CI 1.253-2.973),high surgical stage(OR=1.588,95%CI 1.204-2.095)and large primary cyst(OR=1.139,95%CI1.027-1.263)increased the probability of postoperative recurrence. High Hb(OR=0.982,95%CI 0.967-0.999),postoperative drug therapy(OR=0.220,95%CI 0.126-0.384)and postoperative childbirth(OR=0.507,95%CI 0.290-0.887)reduced the probability of postoperative recurrence. The postoperative recurrence of unilateral primary OMA was more likely to occur on the primary side,and the recurrence of bilateral primary OMA was more likely to be on the left side.ConclusionsCombination with uterine fibroids,bilateral OMA,being accompanied by clinical symptoms,surgery during menstrual secretion,high surgical stage,and large primary cyst are independent risk factors for postoperative recurrence of OMA. High Hb,postoperative drug therapy and postoperative childbirth are protective factors for postoperative recurrence. There is a certain correlation between primary OMA and recurrent OMA concerning the lateral distribution.

【基金】 大健康研究院健康大数据与群体医学研究所专项资金(JKS2022009)~~
  • 【文献出处】 中国实用妇科与产科杂志 ,Chinese Journal of Practical Gynecology and Obstetrics , 编辑部邮箱 ,2026年01期
  • 【分类号】R711.71
  • 【下载频次】50
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