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原发性高嗜酸性粒细胞增多综合征致多发性急性脑梗死1例报告
Multiple acute cerebral infarctions caused by primary hypereosinophilic syndrome: A case report
【摘要】 原发性高嗜酸性粒细胞增多综合征表现为外周循环中的嗜酸性粒细胞克隆性增生>1.50×10~9/L并伴有其他组织器官损伤,目前国内关于该疾病导致脑梗死的病例报道较少。本文报道1例由该疾病引起的多发性急性脑梗死患者,以腹痛起病,伴有肌钙蛋白增高,后出现双侧的前、后循环区域多发性急性脑梗死,通过激素和伊马替尼治疗后临床症状得到明显改善。本报告旨在提高临床医生对高嗜酸性粒细胞增多综合征的警惕,尽早明确诊断并积极治疗改善预后。
【Abstract】 Primary hypereosinophilic syndrome manifests as clonal proliferation of eosinophils(>1. 50×10~9/L) in peripheral circulation, accompanied by damage to other tissues and organs, and at present, there are relatively few case reports on cerebral infarction caused by this disease in China. This article reports a case of multiple acute cerebral infarctions caused by this disease, in which the patient had abdominal pain as the initial presentation, accompanied by an increase in troponin. Then the patient developed multiple acute cerebral infarctions in the anterior and posterior circulation regions at both sides, and clinical symptoms were significantly improved after treatment with hormones and imatinib. This case report aims to improve the awareness of hypereosinophilic syndrome among clinicians. A confirmed diagnosis should be made as early as possible and treatment should be performed actively to improve prognosis.
【Key words】 Hypereosinophilic syndrome; Acute cerebral infarction; Imatinib;
- 【文献出处】 中风与神经疾病杂志 ,Journal of Apoplexy and Nervous Diseases , 编辑部邮箱 ,2026年05期
- 【分类号】R743.33;R557.5
- 【下载频次】27