【摘要】 目的 探讨渐进性抗阻训练（PRT）对老年2型糖尿病（T2DM）患者肌肉力量、躯体功能及血管功能的影响。方法 本研究为随机对照试验。采用便利抽样法选取2025年1月—6月在社区招募的32例老年T2DM患者作为研究对象，采用随机数字表法将其分为对照组和试验组，各16例。对照组接受健康教育，试验组在健康教育基础上实施PRT。比较干预前后2组肌肉力量、躯体功能及血管功能的差异。分别使用意向性（ITT）分析和方案依从性（PP）分析评估干预效果。结果 4周时试验组与对照组各脱落1人，8周时试验组脱落2人，最终试验组13例、对照组15例完成该研究。干预前，2组握力（左、右手）、简易体能状况量表（SPPB）得分、臂踝脉搏波传导速度（baPWV）、踝肱指数（ABI）比较差异均无统计学意义。干预后，试验组握力（左、右手）、SPPB得分较干预前提高，且高于对照组（P均<0.05）；干预前后，试验组与对照组baPWV、ABI比较差异均无统计学意义；PP分析与ITT分析结果一致。结论应用12周PRT对老年T2DM患者进行干预，可有效提高其肌肉力量，改善其躯体功能。更多还原

【Abstract】 Objective To investigate the effects of progressive resistance training(PRT) on muscle strength, physical function, and vascular function in elderly patients with type 2 diabetes mellitus(T2 DM). Methods This was a randomized controlled trial. A total of 32 elderly patients with T2 DM were recruited from the community between January and June 2025 using convenience sampling method. They were randomly divided into a control group and an experimental group using a random number table, with 16 cases in each group. The control group received health education, while the experimental group received PRT in addition to health education. Differences in muscle strength, physical function, and vascular function were compared between the two groups before and after the intervention. Intention-to-treat(ITT) and perprotocol(PP) analyses were used to evaluate the intervention effects. Results At week 4, one patient dropped out from the experimental group and one from the control group. At week 8, two patients dropped out from the experimental group. Finally, 13 patients in the experimental group and 15 patients in the control group completed the study. Before the intervention, there were no statistically significant differences between the two groups in grip strength(left and right hands), Short Physical Performance Battery(SPPB) score, brachial-ankle pulse wave velocity(baPWV), or ankle-brachial index(ABI). After the intervention, the grip strength(left and right hands) and SPPB score in the experimental group were significantly higher than those before the intervention and also higher than those in the control group(all P < 0. 05). No statistically significant differences were found in baPWV or ABI between the two groups either before or after the intervention. The results of PP analysis were consistent with those of ITT analysis. Conclusion A 12-week PRT intervention can effectively improve muscle strength and physical function in elderly patients with T2 DM.更多还原