【摘要】 目的 分析P波时限及P波离散度（Pd）与房颤（AF）射频消融术后复发的相关性。方法 选取本院2023年9月至2025年1月收治的100例首次行射频消融术的AF患者，持续随访至术后6个月，根据患者术后6个月内AF复发情况进行分组，分为早期复发组（术后3个月内复发，n=24）、晚期复发组（术后3～6个月复发，n=18）及未复发组（术后6个月内未复发，n=58）。比较三组P波时限(P_min、 P_max)、 Pd及心功能指标，并分析二者间的相关性。结果 早期复发组与晚期复发组P_min均低于未复发组，P_max、 Pd均高于未复发组（P<0.05）。早期复发组与晚期复发组P_min、 P_max、 Pd比较，差异无统计学意义（P >0.05）。早期复发组与晚期复发组的左心房内径（LAD）高于未复发组，左室射血分数（LVEF）低于未复发组（P<0.05）。早期复发组与晚期复发组LAD、 LVEF比较，差异无统计学意义（P >0.05）。Pearson相关性分析结果显示，P_min与LAD呈负相关，与LVEF呈正相关（r=-0.321、 0.335, P<0.05）; P_max、 Pd与LAD呈正相关（r=0.249、 0.435, P<0.05），与LVEF呈负相关（r=-0.298、-0.416, P<0.05）。结论 射频消融术后AF复发患者P_min更低，P_max与Pd更高，且患者P波时限与Pd和心功能指标存在明显关联。临床可通过监测患者术后P波时限与Pd变化情况，预测疾病复发风险，尽早制定相关防范策略。更多还原

【Abstract】 Objective To analyze the correlation between P-wave duration, P-wave dispersion（Pd） and recurrence after radiofrequency ablation for atrial fibrillation（AF）. Methods 100 AF patients undergoing first-time radiofrequency ablation in our hospital from September 2023 to January 2025 were selected, and followed up continuously for 6 months after surgery. According to the recurrence of AF within 6 months after surgery, the patients were divided into early recurrence group（recurrence within 3 months after surgery, n = 24）,late recurrence group（recurrence between 3 and 6 months after surgery, n = 18） and non-recurrence group（no recurrence within 6 months after surgery, n = 58）. The P-wave duration(P_min, P_max), Pd and cardiac function indicators were compared among the three groups, and the correlation between the above indicators was analyzed. Results The P_minof the early recurrence group and late recurrence group were lower than those of the non-recurrence group, and the P_maxand Pd were higher than those of the non-recurrence group（P <0.05）. No statistically significant difference was found in the P_min, P_maxand Pd between the early recurrence group and the late recurrence group（P >0.05）. The left atrial diameter（LAD） of the early recurrence group and late recurrence group were higher than those of the non-recurrence group, and the left ventricular ejection fraction（LVEF） were lower than those of the non-recurrence group（P <0.05）. No statistically significant difference was found in the LAD and LVEF between the early recurrence group and the late recurrence group（P >0.05）. Pearson correlation analysis results showed that P_minwas negatively correlated with LAD, and positively correlated with LVEF（r =-0.321, 0.335, P <0.05）; P_maxand Pd were positively correlated with LAD（r = 0.249, 0.435, P <0.05）, and negatively correlated with LVEF（r =-0.298, 0.416, P <0.05）.Conclusions AF patients with recurrence after radiofrequency ablation have lower P_minand higher P_maxand Pd. Moreover, there is a significant correlation between P-wave duration, Pd and cardiac function indicators. Clinically, monitoring the changes in P-wave duration and Pd after surgery can help predict the risk of disease recurrence and formulate preventive strategies as early as possible.更多还原