【摘要】 脐带血(UCB)自体回输是一种具有重要临床应用前景的围术期血液保护策略，尤其适用于需行心脏直视手术的先天性心脏病(CHD)新生儿。利用分娩时采集的脐带血，将其作为一种天然的自体血液来源，用于术中预充体外循环旁路回输(CPB)至新生儿体内，从而有效减少甚至避免异体血制品的使用。推动该技术的规范化应用，对降低输血相关并发症和提升先天性心脏病新生儿围术期安全性及生存质量具有积极意义。本文基于国内外现有文献，结合我国国情及临床实践，系统阐述了UCB自体回输在先心病产前产后一体化诊疗模式中的应用方法，明确适应证与禁忌证，重点构建了UCB的采集、储存、质量控制、回输、不良反应及处理措施的全流程管理方案。更多还原

【Abstract】 Umbilical cord blood(UCB) autotransfusion is a perioperative blood conservation strategy with considerable clinical potential, particularly for neonates with congenital heart disease(CHD) who require openheart surgery. This technique utilizes cord blood collected at birth as a natural autologous blood source for priming the cardiopulmonary bypass(CPB) circuit and for intraoperative transfusion, effectively reducing or even eliminating the need for allogeneic blood products. The standardized implementation of this approach has positive implications for reducing transfusion-related complications and improving perioperative safety and quality of life in children with CHD. Drawing on current domestic and international literature and taking into account China’s healthcare context and clinical practices, this article systematically elaborates on the application of UCB autotransfusion within an integrated peripartum management model for CHD. It outlines the indications and contraindications, emphasizing the establishment of a comprehensive management protocol covering UCB collection, storage, quality control, transfusion, and adverse reaction management.更多还原