【摘要】 目的 本研究旨在对比常规抗抑郁药物治疗与常规抗抑郁药物联合辩证行为疗法的临床效果，明确辩证行为疗法对青少年抑郁症患者非自杀性自伤的干预价值。方法 选取本院收治的青少年抑郁症患者（116例），选例时间：2023年1月～2025年6月；对研究对象进行分组，并参照随机数字表法，将其分为A、B两组，且每组根据1∶1比例分为58例。对照组：常规抗抑郁药物；干预组：对照组基础上+辩证行为疗法，所有组患者均持续治疗12周，并统计对比各项指标结果数据。结果 干预组总有效率高于对照组，自伤行为总发生率低于对照组；与治疗前相比，治疗后两组Connor-Davidson心理弹性量表（CD-RISC）评分、自尊量表（SES）评分均升高，且干预组更高；两组汉密尔顿抑郁量表（HAMD）、Zarit照顾者负担量表（ZBI）评分均降低，且干预组更低，以上均P<0.05。结论 辩证行为疗法联合常规抗抑郁药物治疗青少年抑郁症患者，可显著提升治疗总有效率，降低非自杀性自伤行为发生率，更有效地改善患者心理弹性、缓解抑郁情绪、提升自尊水平并减轻家属照顾负担。更多还原

【Abstract】 Objective This study aims to compare the clinical effects of conventional antidepressant therapy alone versus conventional antidepressants combined with dialectical behavior therapy(DBT), clarifying the intervention value of DBT for non-suicidal self-injury in adolescent depression patients. Methods A total of 116 adolescent depression patients(116 cases) admitted to our hospital were selected from January 2023 to June 2025. The subjects were divided into control group and intervention group according to a random number table method, with each group further subdivided at a 1∶1 ratio(58 cases per group). Control group received conventional antidepressant therapy, while intervention group received DBT in addition to Control group ’s treatment. All patients underwent continuous treatment for 12 weeks, and the results of various indicators were statistically compared. Results intervention group demonstrated a higher overall effective rate than Control group, with a lower incidence of self-injurious behavior. Compared to pre-treatment, both groups showed elevated Connor-Davidson resilience scale(CD-RISC) and self-esteem scale(SES) scores posttreatment, with Intervention control group chieving higher scores. Both groups exhibited reduced Hamilton depression rating scale(HAMD) and Zarit burden interview(ZBI) scores, with intervention group showing greater reductions(all P<0.05). Conclusion Combining DBT with conventional antidepressant therapy for adolescent depression patients significantly improves overall treatment efficacy, reduces the incidence of non-suicidal selfinjury, and more effectively enhances psychological resilience, alleviates depressive symptoms, boosts self-esteem, and reduces caregiver burden.更多还原