【摘要】 迟发性性腺功能减退症(LOH)是一种与年龄增长及雄激素不足相关的男科疾病，多见于中老年男性。LOH的临床症状与抑郁症部分相似，单凭症状很难区分，为临床诊疗造成了一定困扰。现代医学治疗LOH主要采取睾酮替代疗法(TRT)或抗抑郁药物治疗，但TRT对LOH患者抑郁症状的改善尚存一定争议，且抗抑郁药物对性功能有抑制作用。通过中医药治疗LOH，补肾疏肝，随症治之，可规避西药的不良反应及风险，缩短疗程，从整体上改善LOH患者的性功能症状与抑郁症状。本文旨在探讨中医药干预LOH患者抑郁症状的临床意义、优势及辨治思路，为临床诊疗提供参考。更多还原

【Abstract】 Late-onset hypogonadism( LOH),an andrology disease associated with age advancement and androgen deficiency,is frequently observed in middle-aged and elderly men. The clinical manifestations of LOH overlap with those of depression,making it challenging to differentiate solely based on symptoms and causing certain perplexities in clinical diagnosis and treatment. In contemporary medical therapeutics,the main approaches include testosterone replacement therapy( TRT) or the antidepressant drugs treatment. However,there remains certaincontroversyregarding the improvement of depressive symptoms in LOH patients through TRT,while antidepressant drugs have an inhibitory impact on sexual function. Employing traditional Chinese medicine for treatment,nourishing the kidneys and soothing the liver, and treating based on individual symptoms,can circumvent the adverse reactions and risks of western medicine,shorten the treatment course,and comprehensively ameliorate the sexual and depressive symptoms of LOH patients. This paper aims to explore the clinical significance,advantages,and syndrome differentiation-based treatment approach of traditional Chinese medicine intervention for depressive symptoms in patients with LOH,providing a reference for clinical diagnosis and treatment.更多还原