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女性性欲低下治疗药物的研发进展

Research progress in the development of drugs for treating low sexual desire in women

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【作者】 罗澜; 付彤; 黄晶晶; 李华芳; 沈一峰;

【Author】 LUO Lan;FU Tong;HUANG Jingjing;LI Huafang;SHEN Yifeng;Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine;Mental Health Center Affiliated To Tongji University;Shanghai Clinical Research Center for Mental Health;Shanghai Key Laboratory of Psychotic Disorders;

【通讯作者】 沈一峰;

【机构】 上海交通大学附属精神卫生中心; 同济大学附属精神卫生中心; 上海市精神心理疾病临床医学研究中心; 上海市重性精神病重点实验室;

【摘要】 女性性欲低下是最常见的女性性功能问题,但缺乏疗效可靠的药物治疗手段。尽管目前在国际上已获批诸多药物治疗女性性欲低下障碍,但我国尚无药物正式获批。为促进女性性健康临床服务,本文分别综述了单胺通道类(氟班色林、丁螺环酮、曲唑酮、安非他酮等)、黑皮质素通道类(布美兰肽)、激素类(睾酮等)、多肽类(奥瑞奈肽)及中草药类药物的研发进展及临床应用。

【Abstract】 Low sexual desire in women is the most common female sexual problem,and there is a lack of pharmacotherapies with proven efficacy. Although several therapeutic drugs have been approved internationally for the treatment of hypoactive sexual desire disorder( HSDD) in women,no medication has been formally approved in China yet. To promote clinical services for women’s sexual health,this paper reviews the research progress and clinical applications of drugs acting on various pathways,including monoamine pathway agents( flibanserin,buspirone,trazodone,bupropion),the melanocortin pathway agents( bremelanotide),hormonal agents( testosterone),peptides( orenetide),and traditional Chinese herbal medicines.

【关键词】 女性; 性欲低下; 药物;
【Key words】 Women; Low sexual desire; Drug;
  • 【文献出处】 中国性科学 ,Chinese Journal of Human Sexuality , 编辑部邮箱 ,2026年01期
  • 【分类号】R711.77
  • 【下载频次】47
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