【摘要】 目的 分析超声检查在中枢性性早熟（CPP）女童中的应用价值。方法 选取2022年1月至2024年6月于漯河市妇幼保健院就诊的138例CPP女童为CPP组，另选同期138名行健康体检的女童为对照组。2组行盆腔超声检查，比较女童子宫和卵巢的长径、横径、前后径及容积，子宫内膜厚度、最大卵泡直径等参数；采用受试者工作曲线（ROC）分析超声参数在CPP女童中的诊断效能。结果 与对照组相比，CPP组女童的子宫长径[（2.73±1.22）cm与（1.79±1.92）cm,t=4.854,P<0.001]、卵巢长径[（2.92±0.39）cm与（2.63±0.44）cm,t=5.794,P<0.001]、子宫横径[（1.59±0.59）cm与（1.19±0.44）cm,t=6.384,P<0.001]、卵巢横径[（1.93±0.12）cm与（1.76±0.22）cm,t=7.969,P<0.001]、子宫前后径[（1.38±0.52）cm与（0.82±0.41）cm,t=9.934,P<0.001]、卵巢前后径[（1.18±0.44）cm与（1.10±0.26）,t=3.908,P<0.001]、子宫容积[（3.14±1.12）ml与（0.93±1.11）ml,t=6.464,P<0.001]、卵巢容积[（3.48±1.11）ml与（2.67±0.85）ml,t=6.806,P<0.001]、最大卵泡直径[（0.79±0.14）cm与（0.67±0.11）cm,t=7.918,P<0.001]、宫体/宫颈[（1.62±0.71）与（0.76±0.28）,t=13.237,P<0.001]更大，子宫内膜厚度更厚[（1.19±0.22）mm与（0.98±0.26）mm,t=7.243,P<0.001]，直径>4 mm的卵泡数量更多[（2.85±0.85）个与（1.49±0.51）个，t=16.117,P<0.001]。子宫容积、子宫内膜厚度、宫体/宫颈、卵巢容积、最大卵泡直径、卵泡数量单独及联合诊断CPP女童的ROC曲线下面积为0.888、0.728、0.871、0.719、0.765、0.914、0.977(P<0.05)。结论 子宫超声联合参数、卵巢超声联合参数对CPP具有较高的诊断价值，但联合检测诊断效能更高。更多还原

【Abstract】 Objective To analyze the value of ultrasonography in girls with central precocious puberty(CPP). Methods A total of 138 CPP girls treated in Luohe Maternal and Child Health Hospital from January2022 to June 2024 were selected as the CPP group, and 138 girls who underwent physical examination during the same period were selected as the control group. Pelvic ultrasound was performed in both groups. The long diameter, transverse diameter, anteroposterior diameter and volume of uterus and ovary of girls were calculated and compared; Receiver operating curve(ROC) was used to analyze the diagnostic efficacy of ultrasonic parameters in CPP girls. Results Compared to the control group, the length diameter of uterus and ovary [uterws:(2.73±1.22)cm vs.(1.79±1.92)cm, t=4.854, P<0.001; ovary:(2.92±0.39)cm vs.(2.63±0.44)cm, t=5.794, P<0.001],transverse diameter [uterus:(1.59±0.59)cm vs.(1.19±0.44)cm, t=6.384, P<0.001; ovary:(1.93±0.12)cm vs.(1.76±0.22)cm, t =7.969, P <0.001], anteroposterior diameter [uterws:(1.38 ±0.52)cm vs.(0.82 ±0.41)cm, t =9.934, P <0.001; ovary:(1.18±0.44)cm vs.(1.10±0.26)cm, t=3.908, P<0.001], volume [uterws:(3.14±1.12)ml vs.(0.93±1.11)ml, t=6.464, P <0.001; ovary:(3.48 ±1.11)ml vs.(2.67 ±0.85)ml, t =6.806, P <0.001], maximum follicle diameter[(0.79±0.14)cm vs.(0.67±0.11)cm, t=7.918, P<0.001], uterine body/cervix [(1.62±0.71) vs.(0.76±0.28), t=13.237,P<0.001]were greater, endometrium is thicker [(1.19±0.22)mm vs.(0.98±0.26)mm, t=7.243, P<0.001], follicles with diameters >4 mm were more numerous [(2.85 ±0.85) vs.(1.49 ±0.51), t =16.117, P <0.001]. Uterine volume,endometrial thickness, uterine body/cervix, ovarian volume, maximum follicle diameter, and number of follicles were 0.888, 0.728, 0.871, 0.719, 0.765, 0.914, and 0.977 in girls diagnosed with CPP alone and in combination(P <0.05). Conclusion The combined parameters of uterine ultrasound and ovarian ultrasound have high diagnostic value for CPP, but the combined detection has higher diagnostic efficiency.更多还原