【摘要】 胆管支架植入是治疗胆石症以及胆管梗阻的重要手段之一，也是解决肝门部胆管癌症等恶性肿瘤引起的胆管堵塞问题的重要治疗措施。植入类支架的力学性能、生物安全性等需满足较高标准的要求，目前市场上的胆管支架主要是不可降解支架，分为金属支架与高分子支架，两类支架各有优劣，但都面临着因其不可降解而引起术后并发症或微生物聚集引发炎症等问题。因此，包括镁合金支架在内的可降解胆管支架与纳米银表面涂层等受到人们的关注，各种新型胆管支架及表面涂层陆续出现并逐渐投入临床使用。本文主要介绍了胆管支架的研究现状，分析比较了不同胆管支架材料的优劣，总结了部分新型胆管支架及表面涂层的研究进展，并对胆管支架及其表面处理的未来发展进行了展望。更多还原

【Abstract】 Biliary stent implantation is one of the important methods to treat cholelithiasis, biliary stricture and biliary obstruction, and also an important measure to solve the obstruction of bile duct caused by malignant tumor including cancer of hilar bile duct.Implantable stents are required to adhere to high standards in terms of mechanical performance and biological safety.Currently, the majority of biliary stents commercially available are non-degradable.They can be broadly classified into metal stents and polymer stents, each presenting a distinct set of advantages and limitations.And both of them are facing the problems of postoperative complications caused by non-degradation of stents and inflammation caused by microbial aggregation.Therefore, biodegradable biliary stent including magnesium alloy stent and nano-silver coating have attracted much attention, various new types of biliary stents and surface coatings are emerging and being gradually introduced into clinical practice.In this paper, the research status of biliary stents is introduced, the advantages and disadvantages of different material biliary stents are analyzed and compared, and the research progress of some new types of biliary stent and their surface coating is summarized, the future development of biliary stents and their surface treatment is prospected.更多还原