【摘要】 颈部肌张力障碍（cervical dystonia,CD）是最常见的成人发作性局灶性肌张力障碍，可显著损害患者的自理能力及生活质量。目前的主要治疗手段包括肉毒毒素治疗、药物治疗、手术治疗、物理治疗、心理治疗以及中医药特色疗法等。本文对CD现有治疗方式进行文献回顾，总结了不同干预措施的疗效、安全性及局限性。研究发现，现有治疗手段对于CD运动症状的干预效果较为确切，然而针对抑郁和焦虑等非运动症状的疗效评价与临床关注仍存在明显不足。未来应致力于探索整合药物、手术、康复及心理干预的多模态个体化治疗方案，以实现对患者治疗需求的精准匹配以及生活质量的全面提升。更多还原

【Abstract】 Cervical dystonia(CD) is the most common type of adult-onset focal dystonia, which can significantly impair patients’ self-care ability and quality of life. Current mainstream therapeutic approaches include botulinum toxin therapy, pharmacotherapy, surgical treatment, physical therapy, psychological therapy, and characteristic therapies of traditional Chinese medicine(TCM). This paper conducts a literature review on the existing therapeutic modalities for CD and summarizes the efficacy, safety and limitations of different interventional measures. It is found that the existing therapies exert definite effects in managing the motor symptoms of CD, whereas obvious deficiencies remain in the efficacy evaluation and clinical attention to non-motor symptoms such as depression and anxiety. Future research should focus on exploring multimodal individualized treatment regimens integrating pharmacotherapy, surgery, rehabilitation and psychological intervention, so as to achieve precise matching of patients’ treatment needs and comprehensive improvement of their quality of life.更多还原