【摘要】 目的：探讨运动疗法对功能性消化不良餐后不适综合征患者疗效及胃动力的影响。方法：前瞻性纳入石河子大学第一附属医院消化内科门诊诊断为功能性消化不良餐后不适综合征患者58例，随机分为运动组和对照组。对照组接受药物治疗，运动组在药物治疗基础上增加中等强度运动干预。治疗6周后，评估2组患者的总有效率，比较症状评分（Nepean Dyspepsia Symptom Index, NDSI）及生活质量评分（Nepean Dyspepsia Life Quality Index,NDLQI）的变化，并通过胃十二指肠超声造影检查评估各时间点（30、60、90、120 min）胃排空率及胃半排空时间等胃动力指标的变化情况。结果：运动组（25例）和对照组（26例）受试者均完成了6周的临床干预。治疗后运动组总有效率为84.00%，对照组总有效率为46.15%，运动组显著高于对照组（P<0.05）。2组NDLQI评分治疗后较治疗前均升高，运动组较对照组升高明显（P<0.05）。治疗前运动组与对照组30、60、90、120 min时间点胃排空率及胃半排空时间未见显著差异（P>0.05），治疗后运动组较对照组各时间点胃排空率加快、胃半排空时间缩短（P<0.05）。运动组治疗后较治疗前各时间点胃排空率加快、胃半排空时间缩短（P<0.05）；对照组治疗后较治疗前60 min时间点胃排空率减慢（P<0.05）,30、90、120 min时间点胃排空率及胃半排空时间比较差异无统计学意义（P>0.05）。结论：中等强度运动疗法可有效改善功能性消化不良餐后不适综合征患者的临床症状，提升其生活质量，并促进胃排空。更多还原

【Abstract】 Objective: To investigate the effect of exercise therapy on clinical outcomes and gastric motility in patients with functional dyspepsia with postprandial distress syndrome(PDS). Methods: A prospective study was conducted including 58 patients diagnosed with functional dyspepsia with PDS at the Gastroenterology Clinic of the First Affiliated Hospital of Shihezi University. Patients were randomly divided into an exercise group and a control group. The control group received drug therapy, while the exercise group received moderate-intensity exercise inter-vention in addition to medication. After 6 weeks of treatment, the overall response rate was evaluated in both groups. Changes in the Nepean Dyspepsia Symptom Index(NDSI) and Nepean Dyspepsia Life Quality Index(NDLQI) scores were compared. Gastric emptying rate at different time points(30, 60, 90 and 120 min) and gastric half-emptying time were assessed by gastroduodenal contrast-enhanced ultrasonography to evaluate gastric motility. Results: A total of 25 patients in the exercise group and 26 patients in the control group completed the6-week intervention. After treatment, the overall response rate was 84.00% in the exercise group and 46.15% in the control group, which was significantly higher in the exercise group(P<0.05). NDSI scores decreased in both groups after treatment compared with baseline, with a greater reduction observed in the exercise group(P<0.05). NDLQI scores increased in both groups after treatment, with a more significant improvement in the exercise group(P<0.05). Before treatment, there were no significant differences between the two groups in gastric emptying rates at30, 60, 90 and 120 min or in gastric half-emptying time(P>0.05). After treatment, gastric emptying rates at all time points were significantly faster and gastric half-emptying time was shorter in the exercise group than in the control group(P<0.05). In the exercise group, gastric emptying rates increased and gastric half-emptying time dereased significantly after treatment(P<0.05). Conclusion: Moderate-intensity exercise therapy can effectively improve clinical symptoms, enhance quality of life, and promote gastric emptying in patients with functional dyspepsia with postprandial distress syndrome.更多还原