【摘要】 分子印迹聚合物(MIPs)是一类具有优异分子识别性能的功能高分子材料，在与分子识别相关的众多领域展现出重要的应用价值。空心分子印迹聚合物(HMIPs)凭借独特的中空结构，具有密度低、比表面积大、渗透性强等特性；与传统实心MIPs相比，HMIPs通常具有更高的吸附容量、更快的吸附动力学速率及更稳定的溶液悬浮性能，这使其在分离纯化、化学传感及药物传输方面性能更优异。文章综述了HMIPs的制备方法，及其在分离纯化、化学传感和药物控释方面的应用研究进展，并针对当前HMIPs存在的问题，展望其未来发展方向。更多还原

【Abstract】 Molecularly imprinted polymers(MIPs) are a class of functional high-polymer materials with excellent molecular recognition performance, and they have shown significant application value in numerous fields related to molecular recognition. Hollow molecularly imprinted polymers(HMIPs), with their unique hollow structure, possess characteristics such as low density, large specific surface area, and strong permeability. Compared with traditional solid MIPs, HMIPs typically exhibit higher adsorption capacity, faster adsorption kinetics, and more stable suspension performance in solution, making them more outstanding in separation and purification, chemical sensing, and drug delivery. This article reviews the preparation methods of HMIPs and the research progress of their applications in separation and purification, chemical sensing, and controlled drug release. Additionally, it discusses the existing problems of HMIPs and looks forward to their future development directions.更多还原