【摘要】 目的 评价正念能量平衡操（MEBE）在Tourette综合征（TS）患儿中的应用效果。方法 选取2022年6月～2024年6月在新乡市中心医院小儿康复科就诊的74例TS患儿为研究对象，将其按照随机数字表法分为实验组与对照组，每组各37例。两组患儿均接受基于国家临床路径推荐的标准化药物治疗，对照组患儿给予常规干预，实验组患儿在对照组基础上给予MEBE干预。MEBE干预自患儿入组当周（T0）启动，采用“强化（T1）-巩固（T2）-维持（T3）”三阶段结构，结合患儿在院干预与家庭辅助干预双场景开展。两组患儿均干预12周。干预前（T0）及干预后（T3末），分别采用耶鲁综合抽动严重程度量表（YGTSS）、儿童青少年正念量表（CAMM）、斯宾塞儿童焦虑量表（SCAS）、儿童生活质量测定量表-家长代评量表（PedsQL-P）评估两组患儿的抽动症状严重程度、正念水平、焦虑程度、生活质量。结果 干预后（T3末），两组患儿YGTSS运动抽动频率、运动抽动强度、发声抽动频率维度评分较干预前（T0）降低，且实验组低于对照组（P<0.01）；而两组患儿YGTSS运动抽动复杂性、发声抽动强度维度评分与干预前（T0）比较，差异均无统计学意义（P>0.05）。两组患儿CAMM评分较干预前（T0）升高，且实验组高于对照组（P<0.01）。两组患儿SCAS分离焦虑、社交恐惧、广泛性焦虑维度评分较干预前（T0）降低，且实验组低于对照组（P<0.01）；两组患儿SCAS惊恐障碍、躯体伤害恐惧维度评分较干预前（T0）降低（P<0.01），但实验组与对照组比较，差异均无统计学意义（P>0.05）。两组患儿PedsQL-P生理功能、社交功能、学校功能维度评分较干预前（T0）升高，且实验组高于对照组（P<0.01）；而两组患儿PedsQL-P情绪功能维度评分与干预前（T0）比较，差异均无统计学意义（P>0.05）。结论 MEBE干预能显著改善TS患儿的抽动与焦虑症状，提升正念水平和生活质量，干预方案结构清晰、节奏递进，适用于医院与家庭场景展开，具备较好的场地适配性与应用潜力。更多还原

【Abstract】 Objective To evaluate the application effect of mindful energy balance exercise(MEBE)in children with Tourette syndrome(TS).Methods Seventy-four TS children seeing doctors from Jun.2022 to Jun.2024 at pediatric rehabilitation Dept.of Xinxiang Central Hospital were selected as research objects and divided into experimental and control group according to random number table method,with 37 ones in each.Children of both groups received the National Clinical Pathway-based standardized medication,controls did conventional intervention,and experimental group did the MEBE intervention on the basis of controls.The MEBE intervention was started in the week of children’s enrollment(T0),adopting three-stage structure of "intensification(T1)-consolidation(T2)-maintenance(T3)",and was carried out in dual scenarios of in-hospital intervention and family-assisted intervention.Both groups were intervened for 12 weeks.Before(T0) and after(at the end of T3) intervention,the Yale Global Tic Severity Scale(YGTSS),Child and Adolescent Mindfulness Measure(CAMM),Spence Children’s Anxiety Scale(SCAS) and Pediatric Quality of Life Inventory Measurement Models-Parent Proxy Report(PedsQL-P) were used to assess the severity of tic symptoms,mindfulness levels,degrees of anxiety and quality of life of both groups,respectively.Results After intervention(at the end of T3),YGTSS motor tics frequency,motor tics intensity and vocal tics frequency lowered in both groups versus pre-intervention(T0) and those were lower in experimental than control group(P<0.01);pre-(T0) and post-intervention differences in the motor tics complexity and vocal tics intensity in both groups weren’t statistically significant(P>0.05).Scores on the CAMM increased in both groups versus pre-intervention(T0) and those were higher in experimental than control group(P<0.01).Scores on the SCAS separation anxiety,social phobia and generalized anxiety dimension lowered in both groups versus pre-intervention(T0) and those were lower in experimental than control group(P<0.01);scores on panic disorder and fear of physical injury lowered in both groups versus pre-intervention(T0)(P<0.01),but intergroup differences weren’t statistically significant(P>0.05).The PedsQL-P physical,social and school functioning scores increased in both groups versus pre-intervention(T0) and those were higher in experimental than control group(P<0.01);pre-(T0) and post-intervention differences in emotional functioning scores in both groups weren’t statistically significant(P>0.05).Conclusion MEBE intervention can significantly improve tic and anxious symptoms of TS children,elevate mindfulness level and quality of life,intervention regimen has a clear structure and a progressive rhythm and is suitable for both hospital and family scenarios,and has better venue adaptability and application potential.更多还原