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经皮三叉神经半月节球囊压迫术与射频热凝术治疗老年人原发性三叉神经痛的疗效与安全性对比研究

Comparative study of the efficacy and safety of percutaneous balloon compression versus radiofrequency thermocoagulation for primary trigeminal neuralgia in elderly patients

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【作者】 潘立业张全云张宏金施辉

【Author】 PAN Liye;ZHANG Quanyun;ZHANG Hongjin;SHI Hui;School of Medicine, Jiangsu University;

【通讯作者】 施辉;

【机构】 江苏大学医学院南京医科大学第四附属医院疼痛科连云港市第二人民医院疼痛科连云港市第一人民医院神经外科

【摘要】 目的 通过对经皮三叉神经半月节球囊压迫术(PBC)与三叉神经半月节射频热凝术(RFT)治疗老年人原发性三叉神经痛(PTN)的疗效、安全性及并发症的比较分析,为临床治疗决策提供依据。方法 回顾性分析连云港市第二人民医院疼痛科2022年1月—2023年10月收治的78例老年PTN患者的临床资料,依据手术方式分为PBC组40例与RFT组38例,观察术前、术后疼痛评分,总体疗效,并发症及复发率。结果 两组患者术前视觉模拟评分(VAS)差异无统计学意义,术后1 h的VAS评分显著降低(P<0.05),两组间术后1 h的VAS评分比较差异无统计学意义(P>0.05)。PBC组的总有效率为95%,RFT组的总有效率为97.4%,两组总有效率比较差异无统计学意义(P>0.05)。RFT组患者中、重度面部麻木的发生率高于PBC组(P<0.05)。两组术后出现咀嚼无力、角膜反射减退、口腔疱疹的差异无统计学意义(P>0.05)。两组患者术后均有复发,两组比较差异无统计学意义(P>0.05)。结论 PBC与RFT两种术式在治疗老年原发性三叉神经痛方面各有优劣。两者均能有效治疗PTN,面部麻木为两者最常见并发症,PBC在减轻面部麻木程度方面表现较好,但需要患者能耐受全身麻醉手术及承担较高的费用。

【Abstract】 Objective To compare the efficacy,safety,and complications of percutaneous balloon compression(PBC) of the trigeminal semilunar ganglion with percutaneous radiofrequency thermocoagulation(RFT) of the trigeminal semilunar ganglion in elderly patients with primary trigeminal neuralgia(PTN),thereby providing evidence for clinical decision-making.Methods The clinical data of 78 elderly patients with PTN admitted to the Department of Pain,Lianyungang Second People’s Hospital from January 2022 to October 2022 were analyzed retrospectively.According to the surgical method,40 cases were divided into PBC group and 38 cases were divided into RFT group.Preoperative and postoperative visual analogue scale(VAS) pain scores,overall efficacy,complications,and recurrence rates were recorded and analyzed.Results There was no significant difference in preoperative VAS scores between the two groups.At 1 hour postoperatively,VAS scores in both groups decreased significantly(P <0.05),with no significant difference at this time point.The overall effective rate was 95% in the PBC group and 97.4% in the RFT group,with no significant difference(P>0.05).The incidence of moderate to severe facial numbness was higher in the RFT group than in the PBC group(P <0.05).Differences in masticatory weakness,decreased corneal reflex,and oral herpes between groups were not significant(P> 0.05).Recurrences occurred in both groups,with no significant difference in recurrence rates(P> 0.05).Conclusions Both PBC and RFT have their respective advantages and disadvantages in treating elderly patients with PTN.Both procedures effectively relieve pain,with facial numbness being the most common complication.PBC offers better relief of facial numbness but requires general anesthesia and incurs higher costs.

【基金】 连云港市科技项目(JCYJ2306)
  • 【文献出处】 临床神经外科杂志 ,Journal of Clinical Neurosurgery , 编辑部邮箱 ,2026年01期
  • 【分类号】R651.3
  • 【下载频次】15
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