【摘要】 目的 通过冠状动脉CT血管造影检查，观察左前降支(left anterior descending, LAD)浅表型心肌桥与其近端周围脂肪组织参数的相关性。方法 纳入2023年5月-2025年9月就诊于新疆生产建设兵团第五师医院，经冠状动脉CT血管造影检查冠状动脉未见斑块，临床疑诊冠状动脉粥样硬化性心脏病患者295例。根据左前降支有无心肌桥(myocardial bridge, MB)将其分为MB组(n=134)和无MB组(n=161)。比较两组性别、年龄、体质量指数、脂肪衰减指数(fat attenuation index, FAI)和脂肪总体积(fat volume, FV)。采用多元线性回归分析探究MB组性别、年龄、体质量指数和左前降支心肌桥(left anterior descending-myocardial bridge, LAD-MB)长度是否对其近端周围脂肪组织FAI和FV有影响。结果 与无MB组相比，MB组FAI增高、FV降低(P<0.01)。多元线性回归分析显示，MB组LAD-MB长度对FAI有影响(P<0.05),年龄、性别、体质量指数均对FAI无影响(P>0.05);年龄、性别、体质量指数、LAD-MB长度均对FV无影响(P>0.05)。结论 FAI、FV可作为评估MB相关血管炎症的潜在影像学生物标志物。更多还原

【Abstract】 Objective To investigate the correlation between superficial myocardial bridge(MB) of the left anterior descending artery(LAD) and parameters of its proximal perivascular adipose tissue using coronary CT angiography. Methods A total of 295 patients clinically suspected of coronary atherosclerotic heart disease who underwent coronary CT angiography at the Fifth Division Hospital of Xinjiang Production and Construction Corps between May 2023 and September 2025 were enrolled. No coronary plaques were detected on CT angiography. According to the presence or absence of MB in the LAD, the patients were divided into an MB group(n=134) and a non-MB group(n=161). Sex, age, body mass index, fat attenuation index(FAI), and fat volume(FV) were compared between the two groups. Multiple linear regression was used to determine whether sex, age, body mass index, and left anterior descending-myocardial bridge(LAD-MB) length affected proximal perivascular adipose tissue FAI and FV in the MB group.Results Compared with the non-MB group, the MB group had higher FAI and lower FV(P<0.01). Multiple linear regression analysis showed that LAD-MB length was associated with FAI in the MB group(P<0.05), whereas age, sex, and body mass index were not(P>0.05). Age, sex, body mass index, and LAD-MB length were not associated with FV(P>0.05).Conclusion FAI and FV may serve as potential imaging biomarkers for assessing MB-related vascular inflammation.更多还原