【摘要】 为分析代谢功能障碍相关脂肪性肝病的症状、证候及用药之间的关系，通过检索中国知网、万方、维普和中国生物医学文献服务系统4个数据库，筛选建库至2024年12月4日代谢功能障碍相关脂肪性肝病文献的中医医案，使用Excel2016软件录入相关数据并导入古今医案云平台V2.3.9,规范化后进行数据挖掘和分析。结果表明：得到代谢功能障碍相关脂肪性肝病的中医医案88例，常见的临床症状为胁胀、乏力和纳呆；常见的舌象为暗舌和红舌、腻苔和白苔；常见的脉象为弦脉与滑脉；常见的证型为肝郁脾虚证与痰瘀互结证；证素以脾和肝、气虚、痰、湿为主；用药以利水渗湿中药为主；具体用药以茯苓、山楂、白术常见。通过数据分析，乏力和胁胀为主要临床症状，核心药对为白术-茯苓。肝郁脾虚证用柴胡、白芍、茯苓、白术、山楂、泽泻、荷叶、丹参等。痰瘀互结证用茯苓、丹参、山楂、白术、荷叶等。可见代谢功能障碍相关脂肪性肝病以肝郁脾虚、痰瘀互结为主要病机，病性虚实兼夹，其主要治法为疏肝健脾、化痰消瘀。这为代谢功能障碍相关脂肪性肝病的中医辨证论治提供了参考。更多还原

【Abstract】 In order to explore the relationship among clinical symptoms, TCM(traditional Chinese medicine) syndromes and Chinese materia medica of MASLD(metabolic dysfunction-associated steatotic liver disease), China National Knowledge Infrastructure, WanFang Data, VIP Information and SinoMed were used to collect the medical records of MASLD from the establishment of the database to December 04, 2024. Relevant data were entered by using Excel2016 and imported into the ancient and modern medical record cloud platform V2.3.9, normalized for data mining and analysis. The results show that 88 medical records of MASLD are obtained. The common clinical symptoms are hypochondrium fullness, fatigue, indigestion and loss of appetite. The common pictures of the tongue are dark tongue, red tongue, greasy coating and white coating. The common pulse manifestations are stringy pulse and slippery pulse. The common TCM syndromes are the syndrome of liver depression and spleen deficiency as well as the syndrome of phlegm and stasis obstructing the internal. The main TCM syndrome elements are spleen, liver, Qi deficiency, phlegm and dampness. Chinese materia medica are mainly used to clear dampness and promote diuresis. Poria Cocos, Hawthorn and Atractylodes Macrocephala are common Chinese materia medica. Through data analysis, fatigue and hypochondrium fullness are the main clinical symptoms, and the core drug pair is Atractylodes Macrocephala-Poria Cocos. Bupleuri Radix, Paeoniae Radix Alba, Poria Cocos, Atractylodes Macrocephala, Hawthorn, Alisma Orientale, Nelumbinis Folium, Salvia Miltiorrhiza, etc., are used for the syndrome of liver depression and spleen deficiency. Poria Cocos, Salvia Miltiorrhiza, Hawthorn, Atractylodes Macrocephala, Nelumbinis Folium, etc., are used for the syndrome of phlegm and stasis obstructing the internal. It is concluded that the main pathogenesis of MASLD is liver depression and spleen deficiency, phlegm and stasis obstructing the internal. The nature of disease is deficiency and excess syndrome. The main treatment of MASLD is to soothe the liver, strengthen the spleen, and resolve phlegm and blood stasis. It provides a reference for the syndrome differentiation and treatment of MASLD.更多还原