【作者】
黄宇星;
晏晓杰;
刘杏;
吉聪聪;
田文敏;
汤号号;
黎勇;
文艺玲;
樊沛瑶;
王泓力;
郗灿坤;
李中天;
陆天;
游富平;
尹鑫;
陈扬;
【Author】
Yuxing Huang;Xiaojie Yan;Xing Liu;Congcong Ji;Wenmin Tian;Haohao Tang;Yong Li;Yiling Wen;Peiyao Fan;Hongli Wang;Cankun Xi;Zhongtian Li;Tian Lu;Fuping You;Xin Yin;Yang Chen;Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Institute of Advanced Clinical Medicine, Peking University;Department of Obstetrics and Gynecology, Peking University First Hospital;State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences;Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Oncology, Peking University Cancer Hospital &Institute;Beijing Advanced Center of Cellular Homeostasis and Aging-Related Diseases, Institute of Advanced Clinical Medicine, Peking University;Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center;Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University;
【通讯作者】
游富平;尹鑫;陈扬;
【机构】
Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Institute of Advanced Clinical Medicine, Peking University;
Department of Obstetrics and Gynecology, Peking University First Hospital;
State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences;
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Oncology, Peking University Cancer Hospital &Institute;
Beijing Advanced Center of Cellular Homeostasis and Aging-Related Diseases, Institute of Advanced Clinical Medicine, Peking University;
Department of Immunology, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center;
Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University;
【摘要】 <正>Viruses have evolved diverse strategies to propagate between cells. Classical paradigms describe two primary transmission modes:cell-free diffusion, where virions navigate extracellular spaces to initiate new infections, and direct cell-to-cell spread that minimizes exposure to host immunity [1,2]. In recent years, a third mechanism has emerged wherein viruses exploit extracellular vesicles (EVs) as intercellular transmission carriers.更多还原
【基金】 supported by the Ministry of Science and Technology of the People’s Republic of China (2022ZD0212900);the National Natural Science Foundation of China (32300570);the Beijing Natural Science Foundation (5244036);the National Key Research and Development Program of China (2023YFF0613402);the Clinical Medicine Plus X-Young Scholars Project of Peking University (PKU2025PKULCXQ013);the Research Funds from Health@Inno HK Program launched by Innovation Technology Commission of the Hong Kong Special Administrative Region