【摘要】 目的 分析湖南省新报告丙型肝炎病例流行特征，为制定丙型肝炎防治策略提供依据。方法 收集2005—2024年湖南省新报告丙型肝炎病例信息，采用描述性流行病学方法分析流行特征及变化趋势。结果 2005—2024年湖南省报告发病率从2005年的1.79/10万上升至2019年的27.52/10万，后下降至2024年的15.47/10万，报告病例数历年间存在线性变化趋势(χ²_趋势=901.973,r_s=0.062,P<0.05)。年平均报告发病率居前3位的地区是怀化市（43.58/10万）、张家界市（24.47/10万）、衡阳市（19.24/10万）；男女性别比1.20∶1，年平均报告发病率男性（16.76/10万）高于女性（14.82/10万），病例主要集中在40～<70岁年龄组，占67.04%（140 051例），农民118 615例，占56.78%。结论 2005—2024年湖南省新报告丙型肝炎病例呈增长趋势，怀化市、衡阳市、张家界市报告发病率较高，男性、40～<70岁、农民是丙型肝炎防控重点关注人群。更多还原

【Abstract】 Objective To analyze the epidemiological characteristics of newly reported hepatitis C cases in Hunan Province and provide evidence for formulating hepatitis C prevention and control strategies. Methods The data of newly reported hepatitis C cases in Hunan Province from 2005 to 2024 were collected, and descriptive epidemiological methods were used to analyze the epidemiological characteristics and trends. Results From 2005 to 2024, the reported incidence rate in Hunan Province increased from 1.79/10⁵ in 2005 to 27.52/10⁵ in 2019, then declined to 15.47/10⁵ in 2024, with a linear trend in the number of reported cases over the years(χ²_tread=901.973, r_s=0.062, P<0.05). The top three regions with the highest average annual reported incidence rates were Huaihua City（43.58/10⁵）, Zhangjiajie City（24.47/10⁵） and Hengyang City（19.24/10⁵）. The male-to-female ratio was1.20∶1, with the average annual reported incidence rate higher in males（16.76/10⁵） than in females（14.82/10⁵）. Cases were predominantly concentrated in the 40-<70 age group, accounting for 67.04%（140 051 cases）, with 118 615 cases（56.78%） among farmers. Conclusions From 2005 to 2024, the number of newly reported hepatitis C cases in Hunan Province showed an increasing trend, and relatively high reported incidence rates were observed in Huaihua City, Hengyang City and Zhangjiajie City.Males, 40-<70 year age group and farmers are key populations for hepatitis C prevention and control.更多还原