【摘要】 目的 了解2006—2024年漳州市新报告HIV/AIDS病例的流行特征及报告发病率时间变化趋势,为制定针对性的艾滋病防控措施提供科学依据。方法 从中国疾病预防控制信息系统提取2006—2024年现住址为漳州市的HIV/AIDS病例信息，采用SPSS 24.0进行描述流行病学分析，利用Joinpoint回归模型分析HIV/AIDS流行趋势，以95%置信区间计算平均年百分比变化（AAPC）。结果 2006—2024年，漳州市新报告HIV/AIDS病例共2 214例，年均报告发病率为2.35/10万。男女报告发病率比例为3.8∶1(3.67/10万∶0.96/10万；χ~2=129.117,P<0.001)。病例中，15～<50岁组占49.60%(1 098/2 214)，≥50岁组占49.86%(1 104/2 214)；其中≥50岁组年均报告发病率最高，为4.34/10万。主要为性传播，占98.87%(2 189/2 214)，其中异性传播占80.31%(1 778/2 214)、同性传播占18.56%(411/2 214)。病例报告来源包括其它门诊检测，占41.06%(909/2 214)、术前筛查占19.20%(425/2 214)、检测咨询占17.93%(397/2 214)。Joinpoint回归分析显示，2006—2024年漳州市HIV/AIDS病例报告发病率总体呈显著上升趋势（AAPC=16.67%,P<0.001）。结论 漳州市HIV/AIDS处于低流行水平，但报告发病率呈显著上升趋势，尤其是中老年人群。建议加强预防干预、扩大检测和治疗等防控措施，以有效遏制艾滋病疫情传播。更多还原

【Abstract】 Objective To describe the epidemiological characteristics and temporal trend of reported HIV/AIDS incidence in Zhang City Fujian Province, from 2006 to 2024, and to provide a scientific basis for targeted AIDS prevention and control measures. Methods Data on newly reported HIV/AIDS cases with current residence in Zhangzhou City from 2006 to 2024 were extracted from the Chinese disease control and prevention information system. Descriptive epidemiological analysis was conducted using SPSS 24.0, and trends were analyzed using Joinpoint regression model to calculate average annual percent change(AAPC) with 95% confidence intervals. Results From 2006 to 2024, a total of 2 214 newly reported HIV/AIDS cases were identified, with an average annual reported incidence of2.35/100 000. The male-to-female ratio of reported incidence was 3.8∶1(3.67/100 000∶0.96/100 000; χ~2=129.117, P<0.001). Among the cases,15-<50 years accounted for 49.60%(1 098/2 214) and ≥50 years for 49.86%(1 104/2 214), with the highest incidence in the≥50 years group(4.34/100 000). Sexual transmission predominated(98.87%, 2 189/2 214), comprisingheterosexual(80.31%, 1 778/2 214)and homosexual(18.56%, 411/2 214) routes. Case detection sources included other outpatient testing(41.06%, 909/2 214), preoperative screening(19.20%, 425/2 214), and voluntary counseling and testing(17.93%, 397/2 214). Joinpoint regression revealed a significant upward trend in reported incidence from 2006 to 2024(AAPC=16.67%, P<0.001). Conclusions While HIV/AIDS remains at a low epidemic level in Zhangzhou City, the reported incidence is increasing significantly, particularly among middle-aged and older adults. Enhanced prevention interventions, expanded testing, and treatment-as-prevention strategies are warranted to curb further transmission.更多还原