【摘要】 目的 探讨妊娠合并卵巢肿瘤患者的诊断、临床特点及孕期处理对母儿结局的影响。方法 回顾性分析2020年1月至2023年12月郑州大学第一附属医院产科收治的294例妊娠合并卵巢肿瘤患者的临床资料，比较卵巢良恶性肿瘤患者的妊娠结局。结果 294例妊娠合并卵巢肿瘤者，17例(5.8%)通过孕前超声、105例(35.7%)通过孕早期超声、8例(2.7%)通过孕中期、15例(5.1%)通过孕晚期超声诊断，149例(50.7%)通过剖宫产术中诊断。流产20例(6.8%),阴道分娩36例(12.2%),剖宫产238例(81.0%)。238例剖宫产病理结果中，良性肿瘤222例(93.3%),交界性肿瘤11例(4.6%),恶性肿瘤5例(2.1%)。妊娠合并卵巢非良性肿瘤患者的分娩时间、新生儿出生体重少于妊娠合并卵巢良性肿瘤患者(t=4.634,P<0.001;t=3.126,P=0.002),新生儿入住新生儿重症监护室率高于妊娠合并卵巢良性肿瘤患者(t=15.663,P<0.001)。结论 妊娠期卵巢肿瘤多为良性肿瘤，绝大多数无典型的临床症状，不易早期诊断。妊娠合并卵巢非良性肿瘤终止妊娠的时机应根据患者的孕周大小、生育意愿、组织类型、肿瘤分期等而异。更多还原

【Abstract】 Objective To explore the diagnosis, clinical characteristics, and the impact of pregnancy management on maternal and fetal outcomes in pregnant patients associated with ovarian tumor. Methods The clinical data of 294 pregnant patients associated with ovarian tumor admitted to the Department of Obstetrics, the First Affiliated Hospital of Zhengzhou University from January 2020 to December 2023 were retrospectively analyzed, and the pregnancy outcomes of benign and malignant ovarian tumor were compared. Results Among the 294 pregnant patients associated with ovarian tumor, 17(5.8%) cases were diagnosed by ultrasound before pregnancy, 105 cases(35.7%) were diagnosed by ultrasound in early pregnancy, 8 cases(2.7%) were diagnosed by ultrasound in middle pregnancy, 15 cases(5.1%) were diagnosed by ultrasound in late pregnancy, and 149 cases(50.7%) were diagnosed by the cesarean section. 20 cases(6.8%) were abortion, 36 cases(12.2%) were vaginal delivery and 238 cases(81.0%) were cesarean section. Among the 238 cases of cesarean section, 222 cases(93.3%) were benign tumors, 11 cases(4.6%) were borderline tumors and 5 cases(2.1%) were malignant tumors. The gestational days of delivery,the birth weight of neonates in the pregnant patients associated with non-benign ovarian tumor were shorter and lighter than that in the benign tumor patients(t= 4. 634,P<0. 001;t= 3. 126,P=0. 002), and the rate of neonates admitted to the intensive care unit was increased than that in the benign tumor patients(t=15. 663,P<0. 001). Conclusion Ovarian tumor during pregnancy are mostly benign, most of them have no typical clinical symptoms and are not easy to diagnose early. The timing of termination of pregnancy with non-benign ovarian tumor should vary according to the gestational age, fertility intention, tissue type, tumor stage, etc.更多还原