【摘要】 目的 构建基于最佳证据的直立性低血压患者循证护理方案，并将其应用于临床实践中，以期通过科学的方法评估该方案的应用效果。方法 选取2022年5～11月接受治疗的直立性低血压患者作为研究对象。通过随机分组的方式将患者分为试验组和对照组，分别接受循证护理方案和常规护理方案。通过一系列检索、筛选文献，根据文献的研究方法、样本量、结果可靠性等因素进行综合分级评价，形成最佳证据条目，循证小组基于得出的最佳证据，结合临床实践经验和患者需求，构建直立性低血压患者的循证护理方案。比较证据应用前后试验组和对照组直立性低血压患者不耐受症状发生率和不耐受症状严重程度的变化。结果 在证据应用后试验组直立性低血压患者不耐受症状发生率下降，统计分析得出头晕发生率由90.79%下降到54.61%(χ~2=50.134,P<0.001),视力模糊发生率由40.79%下降到23.03%(χ~2=11.037,P=0.001),站立不稳发生率由25%下降到14.47%(χ~2=5.316,P=0.021),心悸发生率由9.21%下降到1.97%(χ~2=7.539,P=0.006),恶心发生率由5.26%下降到0.66%(χ~2=4.122,P=0.042),不耐受症状严重程降低(Z=-10.084,P<0.001),改善情况优于对照组，差异有统计学意义(P<0.05)。结论 通过构建并应用基于最佳证据的直立性低血压患者循证护理方案，成功降低了患者不耐受症状的发生率和严重程度。更多还原

【Abstract】 Objective To develop an evidence-based nursing protocol for patients with orthostatic hypotension and apply it in clinical practice, with the aim of scientifically assessing its application effects.Methods Through a series of literature search and screening, comprehensive grading evaluations were conducted based on factors such as research methods, sample size, and result reliability, leading to the formation of best evidence entries.Based on the derived best evidence, and combined with clinical practice experience and patient needs, an evidence-based nursing protocol for patients with orthostatic hypotension was constructed by the evidence-based team.Patients with orthostatic hypotension treated between May 2022 and November 2022 were selected as the study subjects.Through simple random grouping within the ward, patients were divided into the experimental group and control group, receiving the evidence-based nursing protocol and routine nursing protocol, respectively.Comparisons were made regarding the changes in the incidence and severity of intolerance symptoms in patients with orthostatic hypotension before and after the application between groups.Results After the application of the evidence-based nursing, the incidence of intolerance symptoms in the experimental group significantly decreased, including the dizziness(90.79% vs 54.61%, χ~2=50.134, P<0.001), blurred vision(40.79% vs 23.03%, χ~2=11.037, P=0.001), instability on standing(25% vs 14.47%, χ~2=5.316, P=0.021), palpitations(9.21% vs 1.97%, χ~2=7.539, P=0.006), and nausea(5.26% vs 0.66%, χ~2=4.122, P=0.042).The severity of intolerant symptoms also significantly decreased(Z=-10.084, P<0.001), showing a significant improvement in the experimental group than the control group(P<0.05).Conclusion Developing and applying an evidence-based nursing protocol for patients with orthostatic hypotension effectively reduce the incidence and severity of intolerant symptoms.更多还原