【摘要】 目的 探讨次氯酸钠联合Vitapex糊剂治疗乳牙根尖周炎的临床疗效，为优化儿童牙科治疗提供参考。方法 选取2022年2月至2025年1月河南中医药大学第一附属医院收治的88例乳牙根尖周炎患儿，按随机数表法分为观察组(次氯酸钠联合Vitapex糊剂)和对照组(生理盐水联合Vitapex糊剂)，每组44例。比较两组患儿治疗完成后3个月的临床疗效以及治疗前、根管预备后24 h、根管填充后24 h和治疗完成后1周的疼痛程度[视觉模拟评分(VAS)]；比较两组患儿治疗前、治疗完成后3个月的生活质量[口腔健康影响程度(OHIP-5)]和咀嚼功能；同时比较两组患儿治疗过程中不良事件发生情况。结果 观察组患儿的治疗总有效率为95.45%，明显高于对照组的79.55%，差异有统计学意义(P<0.05)。观察组患儿根管预备后24 h、根管填充后24 h、治疗完成后1周的VAS评分分别为(3.91±0.97)分、(1.92±0.65)分、(1.07±0.29)分，明显低于对照组的(4.85±1.06)分、(2.87±0.79)分、(1.63±0.42)分，差异均有统计学意义(P<0.05)。治疗完成后3个月，观察组患儿的OHIP-5评分为(6.12±1.58)分，明显低于对照组的(8.73±1.95)分，咀嚼效率为(86.15±9.03)%，明显大于对照组的(80.34±7.72)%，差异均有统计学意义(P<0.05)。观察组患儿的不良事件总发生率为13.64%，明显低于对照组的31.82%，差异有统计学意义(P<0.05)。结论 次氯酸钠联合Vitapex糊剂可显著提高乳牙根尖周炎的治疗效果，有效缓解术后疼痛，降低炎症反应，改善患儿生活质量，且安全性良好，值得临床推广。更多还原

【Abstract】 Objective To investigate the clinical efficacy of sodium hypochlorite combined with Vitapex paste in the treatment of periapical periodontitis of deciduous teeth, providing a reference for optimizing pediatric dental treatment. Methods A total of 88 children with periapical periodontitis of deciduous teeth admitted to the First Affiliated Hospital of Henan University of Chinese Medicine from February 2022 to January 2025 were selected and divided into an observation group(sodium hypochlorite combined with Vitapex paste) and a control group(normal saline combined with Vitapex paste) using a random number table method, with 44 cases in each group. The clinical efficacy at 3 months after treatment completion, pain levels(Visual Analogue Scale [VAS]) before treatment, 24 h after root canal preparation, 24 h after root canal filling, and 1 week after treatment completion were compared between the two groups. Quality of life(Oral Health Impact Profile-5 [OHIP-5]) and masticatory function were compared between the two groups before treatment and at 3 months after treatment completion. Additionally, the incidence of adverse events during treatment was compared between the two groups. Results The total treatment effective rate in the observation group was 95.45%,which was significantly higher than 79.55% in the control group(P<0.05). The VAS scores at 24 h after root canal preparation, 24 h after root canal filling, and 1 week after treatment completion in the observation group were(3.91±0.97) points,(1.92±0.65) points, and(1.07±0.29) points, respectively, which were significantly lower than(4.85±1.06) points,(2.87±0.79) points, and(1.63±0.42) points in the control group(P<0.05). At 3 months after treatment completion, the OHIP-5 score in the observation group was(6.12±1.58) points, which was significantly lower than(8.73±1.95) points in the control group, and the masticatory efficiency was(86.15±9.03)%, which was significantly higher than(80.34±7.72)% in the control group, with statistically significant differences(P<0.05). The total incidence of adverse events in the observation group was 13.64%, which was significantly lower than 31.82% in the control group(P<0.05). Conclusion Sodium hypochlorite combined with Vitapex paste can significantly improve the treatment efficacy for periapical periodontitis of deciduous teeth, effectively alleviate postoperative pain, reduce inflammatory reactions, improve the quality of life of children, and has good safety, making it worthy of clinical promotion.更多还原