【摘要】 目的 调查慢性乙型肝炎患者肝纤维化监测依从性现状，并深入分析影响患者进行肝纤维化监测的相关因素。方法 选择2024年2月至2025年5月苏州市第五人民医院接诊治疗慢性乙型肝炎患者为对象，调查肝纤维化监测依从性，分析影响肝纤维化监测依从性相关因素。结果 肝纤维化监测依从率为38.07%;Logistic回归分析结果显示，家庭人均收入（OR=1.636）、合并慢性疾病（OR=2.173）、肝癌家族史（OR=2.802）、乙型肝炎家族史（OR=2.835）、1年内肝纤维化相关健康教育频率（OR=3.670、7.338）、合并非酒精性脂肪肝（OR=3.047）、疾病进展恐惧（OR=2.136）、慢性病自我效能水平（OR=2.153）与慢性乙型肝炎患者肝纤维化监测依从性相关（均P<0.05）。结论 慢性乙型肝炎患者肝纤维化监测依从性欠佳。家庭人均收入、合并慢性疾病等多种因素与监测依从性相关，后续应针对这些影响因素采取措施，提升患者监测依从性，以更好阻断疾病向肝硬化、肝癌方向发展。更多还原

【Abstract】 Objective To investigate the status of adherence to hepatic fibrosis monitoring among patients with chronic hepatitis B and to analyze the factors associated with their monitoring behaviors. Methods A cross-sectional study was conducted among patients with chronic hepatitis B receiving care at the Fifth People′s Hospital of Suzhou from February 2024 to May 2025. Adherence to hepatic fibrosis monitoring was assessed, and its potential influencing factors were analyzed. Results The rate of adherence to hepatic fibrosis monitoring was 38.07%. Logistic regression analysis revealed that several factors were significantly associated with monitoring adherence. These included per capita household income(OR=1.636), presence of comorbid chronic diseases(OR=2.173), a family history of liver cancer(OR=2.802), a family history of hepatitis B(OR=2.835), frequency of health education related to hepatic fibrosis within the past year(OR=3.670 and 7.338 for different frequencies), comorbid nonalcoholic fatty liver disease(OR=3.047), fear of disease progression(OR=2.136), and chronic disease self-efficacy(OR=2.153). Conclusion Adherence to hepatic fibrosis monitoring among patients with chronic hepatitis B is suboptimal. Adherence is associated with a range of factors, including socioeconomic status, comorbidities, family history, health education, fear of disease progression, and self-efficacy. Future interventions should target these determinants to improve monitoring adherence, thereby mitigating the progression to cirrhosis and hepatocellular carcinoma.更多还原