【摘要】 目的 本研究旨在探讨脑卒中合并高血压患者的影响因素及其对降压药的依从性，为高血压患者的脑卒中预防提供针对性干预措施。方法 通过多阶段整群抽样，于2019年12月至2020年12月在河北省9市48个监测点抽取40岁及以上常住人口59 434人。采用非条件logistic回归分析探讨脑卒中合并高血压及对降压药依从性的影响因素。结果 59 434例调查对象中，脑卒中的患病率为4.33%,脑卒中合并高血压的患病率为82.47%。脑卒中合并高血压患者中女性、农村、血脂异常、糖尿病、肥胖和具有脑卒中家族史人群患病率较高(P<0.05)。多因素logistic回归分析结果显示，农村、血脂异常、糖尿病、肥胖、脑卒中家族史的脑卒中患者高血压的发病风险较高，OR值(95%CI)分别为1.29(1.03～1.62)、1.39(1.12～1.72)、1.58(1.25～1.99)、1.61(1.22～2.12)、1.60(1.26～2.04)。在脑卒中合并高血压的患者中，92.71%服用降压药。值得注意的是，女性患者服药依从性更好，OR值(95%CI)为1.46(1.01～2.09)。结论 河北省40岁及以上人群脑卒中合并高血压的患病率较高，高血压人群应尽早降血脂、控血糖、减体重，以预防脑卒中的发生。更多还原

【Abstract】 Objective To investigate the influencing factors of stroke patients with hypertension and their compliance with antihypertensive drugs, and to provide targeted intervention measures for stroke prevention in hypertensive patients. Methods Using the method of multi-stage cluster sampling, a total of 59,434 permanent residents aged 40 and above were selected from 48 monitoring sites in 9 cities of Hebei Province from December 2019 to December 2020.Unconditional logistic regression analysis was used to explore the influencing factors of stroke complicated with hypertension and the compliance of patients with antihypertensive drugs. Results Among the 59 434 subjects, the prevalence rate of stroke was 4.33% and the prevalence rate of stroke complicated with hypertension was 82.47%.The results of univariate analysis showed that the proportion of women, rural areas, dyslipidemia, diabetes, obesity, and people with family history of stroke was higher in stroke patients with hypertension, and the difference was statistically significant(P<0.05).Multivariate logistic regression analysis showed that rural areas, dyslipidemia, diabetes, obesity, and family history of stroke significantly increased the risk of stroke, and the OR(95% CI) values were 1.29(1.03-1.62),1.39(1.12-1.72),1.58(1.25-1.99),1.61(1.22-2.12) and 1.60(1.26-2.04),respectively.Among stroke patients with hypertension, 92.71% of patients took antihypertensive drugs.It was found that women′s compliance with antihypertensive drugs was good, with an OR(95% CI) value of 1.46(1.01-2.09). Conclusion The prevalence rate of stroke complicated with hypertension is high in people aged 40 and above in Hebei Province.Hypertensive people should lower blood lipids, control blood glucose, and lose weight as soon as possible to prevent the occurrence of stroke.更多还原