【摘要】 目的：本研究旨在评估结构脂肪乳三腔袋（STG-TCB）的安全性与短期代谢影响，同时分析围术期肠外营养支持的临床使用情况。方法：通过全国范围内的线上病例调查，收集围术期肠外营养支持病人的基本信息、肠外营养处方和生化检查数据。以谷丙转氨酶（ALT）为安全性指标；以血清白蛋白（ALB）、C-反应蛋白（CRP）与血清甘油三酯（TG）为代谢指标，进行STG-TCB和非STG-TCB营养支持结局的差异分析。结果：肠外营养支持结束后，两组病人的ALT、CRP水平显著降低，ALB显著升高；STG-TCB组TG水平显著降低，而非STG-TCB组TG未发生显著变化。Logistic回归显示，使用STG-TCB、肠外营养支持天数、基线BMI和ALB是围术期病人ALB水平的独立影响因素。结论：STG-TCB组病人血清TG水平升高幅度较小，提示其在脂质代谢调控中可能具有优势，同时，STG-TCB的应用可能与ALB水平升高存在初步关联，表明STG-TCB在营养支持中可能存在一定的临床价值。更多还原

【Abstract】 Objective: This study aims to evaluate the safety and short-term metabolic effects of structured triglyceride three-chamber bags(STG-TCB), and to analyze the current status of parenteral nutrition support in perioperative patients. Methods: Through an online case survey nationwide, collect the basic information, parenteral nutrition prescriptions, and biochemical examination data of patients who receive parenteral nutrition support during the perioperative period. Outcomes were compared between the STG-TCB and non-STG-TCB groups, using alanine aminotransferase(ALT) as the safety indicator, and serum albumin(ALB), C-reactive protein(CRP), and triglycerides(TG) as metabolic indicators. Results: After the completion of parenteral nutrition support, the ALT, and CRP levels of patients in both groups decreased significantly, while ALB increased significantly. The TG level in the STG-TCB group decreased significantly, while there was no significant change in the TG level in the non-STG-TCB group. Logistic regression showed that the addition of STG-TCB, the days of parenteral nutrition support, baseline BMI, and ALB levels were the independent influencing factors affecting the ALB level in perioperative patients. Conclusion: Patients in the STG-TCB group exhibited a smaller increase in serum TG levels, suggesting a potential advantage in regulating lipid metabolism. Simultaneously, the application of STG-TCB showed a preliminary association with elevated ALB levels, indicating possible clinical value in nutritional support.更多还原