【摘要】 目的 基于钆塞酸二钠磁共振成像(MRI)分析肝癌患者术后早期复发的影响因素。方法 2019年1月至2024年10月河南科技大学第一附属医院收治的240例肝癌患者均进行根治术治疗,术后随访12个月,根据随访期间患者复发情况将其分为A组(63例,复发)和B组(177例,未复发)。比较两组临床资料及钆塞酸二钠MRI特征、参数,分析肝癌患者术后早期复发的影响因素。结果 A组肝硬化、门静脉癌栓、动脉期瘤周强化、肝胆特异期瘤周低信号患者占比高于B组,强化包膜患者占比及肿瘤相对增强比低于B组(P<0.05)。肝硬化、门静脉癌栓、动脉期瘤周强化、肝胆特异期瘤周低信号、肿瘤相对增强比较低均为肝癌患者术后早期复发的危险因素(OR=2.951、2.659、4.187、3.607、1.758,P<0.05),强化包膜为肝癌患者术后早期复发的保护因素(OR=0.374,P<0.05)。结论 肝癌患者术后早期复发与钆塞酸二钠MRI特征及参数有关,其影响因素包括肝硬化、门静脉癌栓、强化包膜、动脉期瘤周强化、肝胆特异期瘤周低信号、肿瘤相对增强比较低。更多还原

【Abstract】 Objective To analyze the influencing factors of early postoperative recurrence in patients with liver cancer based on gadoxetic acid disodium magnetic resonance imaging(MRI).Methods From January 2019 to October 2024,240 patients with liver cancer in the First Affiliated Hospital of Henan University of Science and Technology were treated by radical operation,followed up for 12 months after operation,and were divided into group A(63 cases,recurrence) and group B(177 cases,no recurrence).The clinical data and MRI features and parameters of gadoxetic acid disodium were compared between the two groups,and the influencing factors of early postoperative recurrence in patients with liver cancer were analyzed.Results The proportion of patients with cirrhosis,portal vein tumor thrombus,peritumoral enhancement in arterial phase and peritumoral low signal in hepatobiliary specific phase in the group A was higher than that in the group B,while the proportion of patients with enhanced capsule and the relative enhancement ratio of tumors were lower than those in the group B(P<0.05).Cirrhosis,portal vein tumor thrombus,peritumoral enhancement in arterial phase,peritumoral low signal in hepatobiliary phase,and relatively low tumor enhancement were all risk factors for early postoperative recurrence in patients with liver cancer(OR=2.951,2.659,4.187,3.607,1.758,P<0.05).Enhanced capsule was a protective factor for early postoperative recurrence in patients with liver cancer(OR=0.374,P<0.05).Conclusion The early recurrence of patients with hepatocellular carcinoma after operation was related to the characteristics and parameters of gadoxetate disodium MRI.The influencing factors included cirrhosis,portal vein tumor thrombus,enhanced capsule,peritumoral enhancement in arterial phase,peritumoral low signal in hepatobiliary phase,and low relative enhancement of tumor.更多还原