【摘要】 目的 系统评价2000—2025年中国儿童青少年糖尿病患病率及影响因素。方法 计算机检索Web of Science、PubMed、EBSCO、CNKI、WanFang Data和VIP数据库，搜集关于糖尿病患病率及危险因素的研究，检索时限均从建库至2025年1月。由2位研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后，采用Stata 18.0软件进行Meta分析。结果 共纳入18个研究，包括25 754 697例研究对象，其中糖尿病患儿1 456例，中国儿童青少年糖尿病合并患病率为1.6‰[95%CI(1.2‰，2.2‰)]。亚组分析表明，男性患病率为2.8‰[95%CI(1.0‰，5.3‰)]、高中阶段为1.0‰[95%CI(0‰，4.1‰)]、城区为3.1‰[95%CI(2.5‰，3.8‰)]、采用WHO诊断标准为1.9‰[95%CI(0‰，8.4‰)]、Ⅱ型糖尿病为1.6‰[95%CI(0.3‰，3.8‰)]。时间趋势分析显示患病率总体呈波动上升态势。结论 中国儿童青少年糖尿病患病率较高，遗传、肥胖、生活方式为主要影响因素，需针对高危人群制定差异化防控策略，并规范诊断标准以提升监测准确性。更多还原

【Abstract】 Objective To systematic review the prevalence and influencing factors of diabetes among children and adolescents in China from 2000 to 2025. Methods The Web of Science, PubMed, EBSCO, CNKI, WanFang Data and VIP databases were electronically searched to collect studies on the prevalence rate and risk factors of diabetes from inception to January 2025. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies. Meta-analysis was then performed using Stata 18.0 software. Results A total of 18 studies were included, involving 25 754 697 study subjects, including 1 456 children with diabetes. The prevalence of diabetes among Chinese children and adolescents was 1.6‰(95%CI 1.2‰ to 2.2‰). Subgroup analysis showed that the prevalence was 2.8‰(95%CI 1.0‰ to 5.3‰) in males, 1.0‰(95%CI 0‰ to 4.1‰) in the senior high school stage,3.1‰(95%CI 2.5‰ to 3.8‰) in urban areas, 1.9‰(95%CI 0‰ to 8.4‰) for those diagnosed using the WHO diagnostic criteria, and 1.6‰(95%CI 0.3‰ to 3.8‰) for type 2 diabetes. Time trend analysis showed that the prevalence rate overall exhibited a fluctuating upward trend. Conclusion The prevalence of diabetes among children and adolescents in China is high, and heredity, obesity and lifestyle are the main influencing factors. It is necessary to develop differentiated prevention and control strategies for high-risk groups, and standardize diagnostic standards to improve the accuracy of monitoring.更多还原