【摘要】 目的：探究基于子午流注理论的针刺与中药穴位贴敷治疗失眠症的临床效果。方法：选取2018年8月1日～2020年7月31日某院收治的97例失眠症患者作为研究对象，根据治疗方案不同分为对照组（n=48）和观察组（n=49）。对照组采用阿普唑仑片治疗，观察组采用基于子午流注理论进行针刺与中药穴位贴敷治疗，两组均连续治疗4周。比较两组患者睡眠质量、日间嗜睡程度、情绪状态变化、临床疗效和不良反应。结果：治疗后，两组患者匹兹堡睡眠质量指数（PSQI）各因子评分与总分、爱泼沃斯嗜睡量表（ESS）评分、焦虑自评量表（SAS）评分、抑郁自评量表（SDS）评分均降低，且观察组低于对照组（P<0.05）。观察组患者临床治疗总有效率（95.92%）高于对照组（83.33%,P<0.05）。治疗期间，两组患者均未发生不良反应。结论：基于子午流注理论的针刺与中药穴位贴敷可以提高失眠症患者临床疗效和睡眠质量，降低白天嗜睡程度，改善情绪状态，且不发生不良反应，具有一定的临床应用价值。更多还原

【Abstract】 Objective: To explore the clinical efficacy of acupuncture and traditional Chinese medicine(TCM) acupoint application in treating insomnia based on the midnight-noon ebb-flow(Ziwu Liuzhu) theory. Methods: A total of 97 patients with insomnia admitted to a hospital from August 1, 2018, to July 31, 2020, were selected and divided into the control group(n=48) and the observation group(n=49) according to different treatment regimens. The control group was treated with alprazolam tablets, while the observation group received acupuncture and TCM acupoint application based on the Ziwu Liuzhu theory. Both groups were treated continuously for 4 weeks. Sleep quality, daytime sleepiness, emotional state changes, clinical efficacy, and adverse reactions were compared between the two groups. Results: After treatment, scores of all Pittsburgh sleep quality index(PSQI) factors and total score, Epworth sleepiness scale(ESS) score, self-rating anxiety scale(SAS) score, and self-rating depression scale(SDS) score decreased in both groups, with lower scores in the observation group than in the control group(P<0.05). The total clinical effective rate of the observation group(95.92%) was higher than that of the control group(83.33%, P<0.05). No adverse reactions occurred in either group during treatment. Conclusion: Acupuncture and TCM acupoint application based on the Ziwu Liuzhu theory can improve clinical efficacy and sleep quality in insomnia patients, reduce daytime sleepiness, and improve emotional state without causing adverse reactions, which has certain clinical application value.更多还原