节点文献

降香与越南降香挥发油标志性差异成分分析

Compositional Analysis of the Iconic Differential Components of Volatile Oil in Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 杨丽; 宋卓悦; 张丹雁; 曾业达;

【Author】 YANG Li;SONG Zhuoyue;ZHANG Danyan;ZENG Yeda;Huangpu People’s Hospital of Zhongshan;Institute of Biological and Medical Engineering, Guangdong Academy of Sciences;School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine;Guangdong Provincial Hospital of Chinese Medicine Hainan Hospital;

【通讯作者】 张丹雁;

【机构】 中山市黄圃人民医院; 广东省科学院生物与医学工程研究所; 广州中医药大学中药学院; 广东省中医院海南医院;

【摘要】 目的 对比分析降香与越南降香的挥发性成分,筛选二者的差异性成分。方法 采用水蒸气蒸馏法提取挥发油,利用气相色谱-质谱联用法(GC-MS)检测降香与越南降香的挥发性成分;采用主成分分析(PCA)和正交偏最小二乘法-判别分析(OPLS-DA)筛选降香与越南降香间的差异性成分。结果 与降香组比较,越南降香的挥发油提取率为1.60%~4.03%,差异有统计学意义(P<0.05)。GC-MS分析得到降香与越南降香挥发油主要成分分别有19、20个,共有成分18个,主要共有成分有环氧化蛇麻烯Ⅱ、橙花叔醇等。降香与越南降香比较,具有统计学意义的挥发油差异性成分有5个,其中能够鉴别降香与越南降香的标志性差异成分为(+)-β-柏木烯、α-红没药醇、2,10-二甲基-9-十一烯醛。结论 越南降香挥发性成分与降香相似度高,(+)-β-柏木烯、α-红没药醇、2,10-二甲基-9-十一烯醛可作为鉴别降香与越南降香的标志性差异成分。

【Abstract】 Objective The volatile components of Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum were compared and analyzed,and the differential components of the two were screened. Methods The volatile oil of Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum was extracted by steam distillation;the components of the volatile oil were tested by Gas Chromatography-Mass Spectrometer(GC-MS);the Principal Component Analysis(PCA) and Orthogonal Partial Least Squares Discriminant Analysis(OPLS-DA) were used to find out the different components of Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum. Results The extraction rate of volatile oil from Dalbergiae Tonkinensise Lignum was 1.60%-4.03%, which was significantly different from that of Dalbergiae Odoriferae Lignum group(P<0.05). GC-MS analysis showed that there were 19 and 20 main components in the volatile oil of Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum,respectively,and 18 common components. The main common components were epoxidized helicene II and nerolidol. There were five volatile oil components with statistically significant differences between Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum. Among them,(+)-β-cedrene,α-bisabolol and 2,10-dimethyl-9-undecenal were the landmark components that could identify Dalbergiae Odoriferae Lignum from Dalbergiae Tonkinensise Lignum. Conclusion The volatile components of Dalbergiae Tonkinensise Lignum have high similarity with Dalbergiae Odoriferae Lignum.(+)-β-cedrene,α-bisabolol and 2,10-dimethyl-9-undecanal can be used as the marker components to identify Dalbergiae Odoriferae Lignum and Dalbergiae Tonkinensise Lignum.

【基金】 张丹雁全国老药工传承工作室建设项目(国中医药人教函[2024]255号);广东省基础与应用基础研究基金项目(2022A1515010337)
  • 【文献出处】 中药新药与临床药理 ,Traditional Chinese Drug Research and Clinical Pharmacology , 编辑部邮箱 ,2025年03期
  • 【分类号】R284.1
  • 【下载频次】77
节点文献中: 

本文链接的文献网络图示:

本文的引文网络