【摘要】 类风湿关节炎(RA)与抑郁症在临床上常常共病，二者具有共同的危险因素及病理机制。氧化应激是指体内活性氧(ROS)及其相关代谢产物的过度积累与机体抗氧化能力不足之间的失衡，这种失衡可导致组织损伤并引发疾病。氧化应激在RA及抑郁症的病理机制中扮演着重要的角色。该文对氧化应激在RA与抑郁症共病机制中的研究进展作一综述。更多还原

【Abstract】 Rheumatoid arthritis(RA) and depression often become comorbidity in clinical practice, and RA and depression have some common risk factors and pathological mechanisms. Oxidative stress refers to the imbalance between the excessive accumulations of reactive oxygen species in the body and their related metabolites and the insufficient antioxidant capacity of the body. This imbalance can lead to tissue damage and cause diseases. Oxidative stress plays an important role in the pathological mechanisms of RA and depression. In this paper, the research progress in the mechanism of oxidative stress in the comorbidity of rheumatoid arthritis and depression is reviewed.更多还原