【摘要】 上海市胸科医院胸外科食管功能检测已有30多年历史，是我国胸外科唯一拥有食管功能检测的科室。历经3代食管功能检测机器的更新换代，食管腔内24 h pH/阻抗监测可以协助诊断、治疗与之相关的食管良、恶性疾病。得益于食管功能检测，除了常规的各类内镜下抗反流手术，上海市胸科医院近年来在国内率先开展系列针对食管良性疾病的工作及研究，如磁力环、双镜联合和抗反流内镜下新技术等，对疑因胃食管反流引起的间质性肺炎、肺纤维化患者行高分辨率食管测压及24 h pH/阻抗监测，评估患者胃食管反流与间质性肺炎、肺纤维化之间的相关性，为临床提供不同治疗依据甚至外科手术干预。美国使用Bravo胶囊较多，其对于传统测酸测压有明显优势。我们大力呼吁在这一领域开展产学研结合工作，开发具有自主知识产权的“本土制造”。更多还原

【Abstract】 The Department of Thoracic Surgery of Shanghai Chest Hospital has performed esophageal function testing for over 30 years, being the only department of its kind in China with this capability. The pressure testing and 24-hour pH/impedance monitoring of the esophagus is of great help to assist in the diagnosis and treatment of benign and malignant esophageal diseases related to it. Thanks to the esophageal function test, in addition to the routine various endoscopic anti-reflux procedures, our hospital has taken the lead in China in recent years to carry out a series of clinical and research work for benign esophageal diseases, such as the development of magnetic ring, double nedoscopic combination and new anti-reflux endoscopic techniques. In recent years, we have carried out high-resolution esophageal manometry and 24-hour pH/impedance monitoring for patients with interstitial pneumonia and pulmonary fibrosis suspected to be caused by gastroesophageal acid reflux. We can better assess the correlation between gastroesophageal reflux and pulmonary fibrosis, and to provide the different clinical treatments and even surgical interventions. The Bravo capsule is used more often in the United States, and it has obvious advantages over traditional approach for acid measurement. We strongly call for the collaboration between industry and academic institutions in this field, and the development of our own related products with independent intellectual property rights.更多还原