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基于《金匮要略》从正虚、痰湿、血瘀论治原发性肝癌的诊疗

On the diagnosis and treatment of primary liver cancer from the perspectives of healthy qi deficiency, phlegm-dampness, and blood stasis based on the synopsis of the Golden Chamber

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【作者】 魏如薇; 周亚娜; 罗保平; 田晓霞; 陈宏琳;

【Author】 WEI Ru-wei;ZHOU Ya-na;LUO Bao-ping;Hubei University of Chinese Medicine;

【通讯作者】 周亚娜;

【机构】 湖北中医药大学第一临床学院; 湖北省中医院肿瘤科; 湖北时珍实验室; 湖北中医药大学附属医院肿瘤科; 中医肝肾研究及应用湖北省重点实验室(湖北省中医院);

【摘要】 基于《金匮要略》的经典理论,探讨原发性肝癌的病因病机,从正虚、痰湿、血瘀出发,论述中医药在原发性肝癌综合治疗中的应用。原发性肝癌是一种常见的消化道肿瘤,其全球发病率高,预后差,且多数患者确诊时已至中晚期,西医传统疗法效果有限,中医药治疗因此显示出其独特的优势。本文分析了肝癌患者正气亏虚、肝脾肾三脏受损的病理特点,并探讨了痰湿、血瘀在肝癌发生发展中的重要作用。本文通过梳理《金匮要略》中的相关论述和经方,如茵陈蒿汤、大黄蛰虫丸、薯蓣丸和鳖甲煎丸,旨在为原发性肝癌的临床诊疗提供理论指导和实践参考。

【Abstract】 Based on the classic theories of Synopsis of the Golden Chamber, this article delves into the etiology and pathogenesis of primary liver cancer and discusses the application of traditional Chinese medicine(TCM) in the comprehensive treatment of this disease from three perspectives: deficiency of vital qi, phlegm-dampness, and blood stasis. Primary liver cancer is a common digestive tract tumor with a high global incidence rate and poor prognosis. Most patients are diagnosed at the middle to advanced stages, where traditional Western medicine therapies have limited effectiveness. As a result, TCM treatment has demonstrated its unique advantages. This article analyzes the pathological characteristics of primary liver cancer patients, including deficiency of vital qi and impairment of the liver, spleen, and kidney, and explores the significant roles of phlegm-dampness and blood stasis in the development of liver cancer. By reviewing relevant discussions and classical prescriptions in Synopsis of the Golden Chamber, such as Shuyu Pill, Biejiajian Pill, Yinchenhao Decoction, and Dahuang Zhechong Pill, this article aims to provide theoretical guidance and practical references for the clinical diagnosis and treatment of primary liver cancer. Studies have shown that these classical prescriptions can not only improve patients’ symptoms and quality of life but also alleviate adverse reactions associated with Western medicine treatments. Therefore, the rational use of TCM classical prescriptions, combined with modern medical approaches, is of great significance in improving the quality of life and survival rates of patients with primary liver cancer.

【基金】 湖北省重点研发计划项目(No.2023BCB126);湖北省自然科学基金项目(No.2022CFB542);湖北中医药大学“十四五”优秀学科团队建设项目(No.中医校[2022]90号)
  • 【文献出处】 中西医结合肝病杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases , 编辑部邮箱 ,2025年11期
  • 【分类号】R273
  • 【下载频次】126
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