【摘要】 本文以态靶辨治理论为指导，结合中国慢性乙型肝炎(CHB)疾病谱规律和现代药理学研究成果，总结CHB相关肝炎、肝硬化、肝癌可分为“湿毒”“瘀毒”“癌毒”三态，以“高病毒载量、转氨酶异常、肝纤维化、肿瘤指标升高”为典型标靶，以“胁痛/肝区不适、消化道出血、腹水”为典型症靶予以相应靶药及推荐剂量，治疗上以“全程治毒、治络，中后期兼顾治虚”为基本原则，把握疾病态势发展。该体系依据分期、分态、识靶的态靶辨治思路，逐层剖析CHB相关肝炎、肝硬化、肝癌在各阶段的核心病理要素和施治重点，一定程度解决了病毒性肝病孤立辨病、辨证与遣方的问题。更多还原

【Abstract】 Guided by the theory of pattern-target differentiation and treatment, this paper integrates the disease spectrum characteristics of chronic hepatitis B(CHB) in China and pharmacological research findings. It summarizes that CHB-related hepatitis, cirrhosis, and primary liver cancer can be categorized into three patterns: "Shi Du-Yu Du-Ai Du".Typical biomarker targets include "high viral load, abnormal transaminase levels, liver fibrosis, and elevated tumor markers, " while symptomatic targets include "hypochondriac pain/liver region discomfort, gastrointestinal bleeding, and ascites." Corresponding target medications and recommended dosages are proposed. The treatment principle emphasizes "addressing toxicity throughout the course, managing collaterals, and supplementing deficiency in the middle and advanced stages" to control disease progression. Based on the pattern-target differentiation and treatment approach-staging, pattern identification, and target recognition, this system systematically analyzes the core pathological elements and treatment priorities for CHB related hepatitis, liver cirrhosis, and liver cancer at various stages. It partially resolves issues such as isolated disease differentiation, syndrome differentiation, and prescription formulation in viral liver diseases.更多还原