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重度非酒精性脂肪性肝病治疗验案一则

A case report on the treatment of severe non-alcoholic fatty liver disease

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【作者】 于楚楚; 刘巧红; 胡义扬;

【Author】 YU Chu-chu;LIU Qiao-hong;HU Yi-yang;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;

【通讯作者】 刘巧红;胡义扬;

【机构】 上海中医药大学附属曙光医院; 上海中医药大学肝病研究所; 上海中医药大学附属曙光医院临床研究中心; 上海中医药大学教育部肝肾疾病重点实验室; 上海市中医临床重点实验室;

【摘要】 非酒精性脂肪性肝病现已被定义为代谢相关肪性肝病,已成为全球第一大慢性肝病。中医学将其归属于“肝癖”、“肥气”、“胁痛”、“积聚”等范畴。胡义扬教授是上海市名中医,上海中医药大学附属曙光医院主任医师、博士研究生导师,从事中医肝病临床、科研与教学工作30余载,诊治非酒精性脂肪性肝病经验丰富,认为该病的病理依据是“痰、湿、瘀、积”,基本病机是痰瘀互结。祛湿化瘀方是胡义扬教授治疗非酒精性脂肪性肝病痰瘀互结证的经验方,临床疗效显著。笔者有幸跟师学习,现报告1例祛湿化瘀方治疗长期反复发作的重度非酒精性脂肪性肝炎病例,供诸位同道参考。

【Abstract】 Non-alcoholic fatty liver disease(NAFLD), now defined as metabolic dysfunction-associated fatty liver disease(MAFLD), has become the most prevalent chronic liver disease worldwide. In Traditional Chinese Medicine(TCM), it falls under the categories of “Gan Pi”, “Fei Qi”, “Xie Tong”, and “Ji Ju”. Professor Hu Yiyang, a renowned TCM practitioner in Shanghai, serves as Chief Physician at Shuguang Hospital Affiliated to Shanghai University of TCM. With over 30 years of experience in clinical practice, research, and teaching in TCM hepatology, he has extensive expertise in diagnosing and treating NAFLD. Professor Hu proposes that the pathological basis of this disease is “phlegm, dampness, stasis, and accumulation”, with the fundamental pathogenesis being intermingled phlegm and stasis. The Qu Shi Hua Yu Formula is Professor Hu′s empirical prescription for treating NAFLD with the pattern of intermingled phlegm and stasis, demonstrating significant clinical efficacy. We had the privilege of studying under Professor Hu and herein report a case of severe, recurrent non-alcoholic steatohepatitis(NASH) successfully treated with the Qu Shi Hua Yu formula for reference by colleagues.

【基金】 国家自然科学基金项目(No.82204840);上海市2022年度“科技创新行动计划”启明星项目(扬帆专项)(No.22YF1449400)
  • 【文献出处】 中西医结合肝病杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases , 编辑部邮箱 ,2025年09期
  • 【分类号】R259
  • 【下载频次】16
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