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猪戊型肝炎及其诊断方法研究进展

Research advances in swine hepatitis E and its diagnostic methods

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【作者】 黄泽华; 晏意良; 齐先峰; 周东辉; 牛志鹏;

【Author】 HUANG Zehua;YAN Yiliang;QI Xianfeng;ZHOU Donghui;NIU Zhipeng;College of Animal Sciences,Fujian Agriculture and Forestry University;Guangzhou Baiyun District Animal Health Supervision Institute;

【通讯作者】 牛志鹏;

【机构】 福建农林大学动物科学学院; 广州市白云区动物卫生监督所;

【摘要】 猪戊型肝炎是由戊型肝炎病毒(hepatitis E virus, HEV)引起的人畜共患病,在全球多个地区广泛流行。猪戊型肝炎作为一个重要的公共卫生问题,受到世界卫生组织的高度重视。然而,对HEV的检测和防治方面仍存在诸多不足。目前常用检测方法包括聚合酶链式反应(PCR)和酶联免疫吸附试验(ELISA)等,近年来,微滴数字PCR和RT-RPA检测方法也被引入HEV检测中。文章综述了猪戊型肝炎病原学和流行病学的研究进展,对现有检测及诊断方法进行了归纳评价,为猪戊型肝炎的检测和防控提供参考。

【Abstract】 Porcine hepatitis E is a significant zoonotic disease caused by the hepatitis E virus(HEV)and is endemic in various regions.As a critical public health concern,porcine hepatitis E has garnered considerable attention from the World Health Organization.However,significant shortcomings remain in the detection and prevention of HEV.The commonly used detection methods currently include polymerase chain reaction(PCR) and enzyme-linked immunosorbent assay(ELISA).In recent years,droplet digital PCR(ddPCR) and reverse transcription recombinase polymerase amplification(RT-RPA) have also been introduced for HEV detection.This review synthesizes current research advancements in the etiology and epidemiology of swine hepatitis E virus infections,provides a critical evaluation of existing detection methodologies and diagnostic approaches,and provides insights for enhancing HEV surveillance and containment strategies in porcine populations.

【基金】 福建省自然科学基金资助项目(2022J0113);福建省校企产学研合作资助项目(2022N5005)
  • 【文献出处】 中国兽医学报 ,Chinese Journal of Veterinary Science , 编辑部邮箱 ,2025年12期
  • 【分类号】S858.28
  • 【下载频次】18
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