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当归药效物质基础及质量控制技术研究进展

Research progress in the material basis and quality control of Angelica sinensis

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【作者】 张建雨; 高鑫; 余河水; 李正; 宋纹; 赵亮; 章顺楠; 李文龙;

【Author】 ZHANG Jian-yu;GAO Xin;YU He-shui;LI Zheng;SONG Wen;ZHAO Liang;ZHANG Shun-nan;LI Wen-long;College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine;Haihe Laboratory of Modern Traditional Chinese Medicine;National & Local United Engineering Laboratory for TCM Advanced Manufacturing Technology Tasly Pharmaceutical Group Co., Ltd.;Tianjin HongRenTang Pharmaceutical Co., Ltd.;Gansu JoinNative Chinese Traditional Medicine Industry Co., Ltd.;

【通讯作者】 章顺楠;李文龙;

【机构】 天津中医药大学中药制药工程学院; 现代中医药海河实验室; 天士力医药集团股份有限公司中药先进制造技术国家地方联合工程实验室; 天津宏仁堂药业有限公司; 甘肃九州天润中药产业有限公司;

【摘要】 当归是大宗主流中药材之一,主产于甘肃岷县,临床应用广泛。近年来当归相关的研究主要集中于体内外药理活性、谱效关系、方剂配伍、药效物质含量测定、全面质量表征及快速分析、安全性指标等方面。本文对近十年来当归相关的研究进展进行归纳、总结,以期为当归药材的资源开发和临床应用提供参考。

【Abstract】 Angelica sinensis, a main traditional Chinese medicinal herb, is primarily produced in Min County, Gansu Province. It has wide range of clinical applications. In recent years, research on Angelica sinensis has focused on such aspects as in vitro and in vivo pharmacological activities,spectrum-effect relationships, compatibility of herbal formulations, determination of active ingredient content, comprehensive quality characterization, rapid analysis, and safety indexes. This article summarized the research progress in Angelica sinensis over the past decades, to provide reference for resource development and clinical application of Angelica sinensis.

【基金】 定西市科技计划项目(No.DX2021AH04);天津市科技计划项目(No.22ZYJDSS00100)
  • 【文献出处】 中南药学 ,Central South Pharmacy , 编辑部邮箱 ,2025年03期
  • 【分类号】R284.1
  • 【下载频次】285
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