【摘要】 目的 建立气相色谱法测定口腔抑菌液中麝香草酚、薄荷脑、水杨酸甲酯、桉叶油素4种挥发性成分的含量。方法 采用安捷伦CP-1301毛细管柱（30 m×0.32 mm×0.25 μm），载气为高纯氮气（99.999%），进样口和检测器（FID）温度为250℃，分流比30∶1，载气流速1.0 mL·min^-1。采用程序升温，起始温度为80℃，保持1 min，再以10℃·min^-1的速率升温至220℃，保持5 min。结果 麝香草酚、薄荷脑、水杨酸甲酯和桉叶油素的线性范围分别为0.0658～0.3289 mg·mL^-1（r=0.9978），0.0437～0.2185 mg·mL^-1（r=0.9979），0.0582～0.2910 mg·mL^-1（r=0.9979）和0.1065～0.5323 mg·mL^-1（r=0.9976）；4种挥发性成分的回收率均在98%～104%，RSD均小于3.0%。结论 该方法操作简便，准确，重复性好，可用于该口腔抑菌液中4种挥发性成分的同时测定。更多还原

【Abstract】 Objective To establish a gas chromatography to simultaneously determine thymol,menthol,methyl salicylate,and eucalyptol in oral antibacterial solution.Methods Agilent CP-1301 （30 m×0.32 mm×0.25 μm） was used as the capillary column.Nitrogen （99.999%） was used as the carrier gas,and FID as the detector.The inlet temperature and FID detector temperature was 250℃.The split ratio was 30∶1 and the flow rate was 1.0 mL·min^-1.The column temperature program was initially 80℃ （holding for 1 min） and then increased at the rate of 10℃·min^-1 to 220℃ （holding for 5 min）.Results The linearity of thymol,menthol,methyl salicylate,and eucalyptol were 0.0658～0.3289 mg·mL^-1 （r=0.9978）,0.0437～0.2185 mg·mL^-1 （r=0.9979）,0.0582～0.2910 mg·mL^-1 （r=0.9979） and 0.1065～0.5323 mg·mL^-1 （r=0.9976）.The recoveries were between 98% and 104%,with the RSDs all less than 3.0%.Conclusion The method is simple,accurate,and reproducible,which can simultaneously determine 4 volatile components in oral antibacterial solution.更多还原