【摘要】 针对中国畜牧业在“十五五”期间面临的重大动物疫病、人兽共患病、寄生虫病及细菌耐药性等多重挑战，为保障产业与公共卫生安全，本建议提出一套系统性的动物疫病综合防控科技创新战略。在分析中国动物疫病防控现状与瓶颈的基础上，聚焦病原致病机制、人兽共患病防控、寄生虫病防治、细菌耐药性控制及新兽药创制五大领域，规划了关键研究路径与目标，绘制了“十五五”科技攻关蓝图。该蓝图强调以基础研究为支撑，深入解析病原致病与免疫逃逸机制；以关键技术为突破口，重点布局新型疫苗、新兽药及智能化监测诊断体系的研发；并针对寄生虫病和细菌耐药性问题制定专项防控策略。实施本建议有望突破核心技术瓶颈，提升中国动物重大疫病综合防控能力，对保障养殖业可持续发展与公共卫生安全具有重大战略意义，为“十五五”动物防疫工作提供顶层设计指导。更多还原

【Abstract】 In response to multiple challenges facing China’s animal husbandry industry, including major animal diseases, zoonotic diseases, parasitic diseases, and bacterial resistance, the proposal of this study aims to establish a systematic scientific and technological innovation strategy for the comprehensive prevention and control of animal diseases during the ’15^thFive-Year Plan’ period, thereby safeguarding industrial and public health security. By analyzing the current situation and bottlenecks in animal disease prevention and control in China, the study focuses on five key areas: pathogenic mechanisms, zoonotic diseases, parasitic diseases,bacterial resistance, and the development of new veterinary drugs, outlining core research pathways and objectives. A blueprint for scientific and technological during the ’15^thFive-Year Plan’ period is proposed.Basic research focuses on pathogenic mechanisms and immune evasion strategies, while key technological initiatives include the development of novel vaccines, new veterinary drugs, and intelligent monitoring and diagnostic systems. Specific strategies are also outlined for addressing parasitic diseases and bacterial resistance. The implementation of this proposal is expected to achieve breakthroughs in core technologies,enhance China’s comprehensive capacity for major animal disease prevention and control, and hold significant strategic importance for ensuring the development of the breeding industry and public health security. It provides a top-level design for animal disease prevention efforts during the ’15^th Five-Year Plan’ period.更多还原