【摘要】 目的 探讨光学相干断层扫描(optical coherence tomography, OCT)检测黄斑区视网膜血管密度及厚度在青少年近视眼中的应用价值。方法 选取100例近视眼青少年作为研究对象，设为研究组，另取同期50例视力正常的青少年体检者作为对照组。2组青少年均接受OCT检查，对比2组黄斑区视网膜血管密度及厚度。此外，将研究组青少年按照近视度数分为低度组(n=45)、中度组(n=41)及高度组(n=14),对比3组黄斑区视网膜血管密度及厚度。结果 研究组黄斑区表层及深层微血管密度均高于对照组(P<0.05)。研究组黄斑中心区、内环鼻侧视网膜厚度均高于对照组，而其他部位视网膜厚度均低于对照组(P<0.05)。低度组、中度组、高度组黄斑区表层及深层微血管密度均呈逐渐升高趋势，且经单因素方差分析证实，各组间差异有统计学意义(P<0.05)。低度组、中度组、高度组黄斑中心区、内环鼻侧视网膜厚度呈逐渐升高趋势，而其他部位视网膜厚度呈逐渐降低趋势，且经单因素方差分析证实，各组间差异有统计学意义(P<0.05)。结论 OCT可及时发现黄斑区病变，为青少年近视眼诊治提供指导依据。更多还原

【Abstract】 Objective To investigate the application value of optical coherence tomography(OCT)in the detection of macular retinal vascular density and thickness in adolescent myopia.Methods A total of 100 adolescents with myopia were selected as the study group, and 50 adolescents with normal vision as the control group.Both groups of adolescents underwent OCT examination, and the retinal vascular density and thickness in the macular area were compared between the two groups.In addition, the adolescents in the study group were divided into low group(n=45),moderate group(n=41)and high group(n=14)according to the degree of myopia, and the retinal vascular density and thickness of the macular area were compared among the three groups.Results The microvascular density of the superficial and deep layers of the macular area in the study group was higher than that in the control group(P<0.05).The retinal thickness of the central macular area and the nasal side of the inner ring in the study group was higher than that in the control group, while the retinal thickness of other parts was lower than that in the control group(P<0.05).The microvascular density of the surface and deep layers of the macular area in the low, medium and high groups showed a gradual increase trend, and the one-way analysis of variance confirmed that the differences between the groups were statistically significant(P<0.05).The retinal thickness of the central macular area and the nasal side of the inner ring in the low group, the moderate group and the high group showed a gradually increasing trend, while the retinal thickness of other parts showed a gradually decreasing trend.The difference between the groups was statistically significant confirmed by one-way analysis of variance(P<0.05).Conclusion OCT can detect macular lesions in time and provide guidance for the diagnosis and treatment of juvenile myopia.更多还原